Postdoctoral Research Fellow (Alenghat) Gut microbiome immunobiology

CO00 Children's Hospital Medical Center; United States; On-site; USD 65,000 - 90,000; Full time

Job summary

Cincinnati Children's Hospital Medical Center is seeking a highly motivated postdoctoral scientist to join the Immunobiology Department. The position focuses on epigenetics, host-microbe interactions, and intestinal biology, with emphasis on microbiota, mucosal homeostasis, and inflammatory diseases.

The candidate should have expertise in molecular biology, mouse handling, and intestinal physiology, with bioinformatics or gnotobiotics experience desirable.

Qualifications

• PhD/MD or equivalent required.
• Experience in molecular biology, mouse handling, and intestinal physiology/mucosal immunology.
• Bioinformatics and/or gnotobiotics experience desirable.

Responsibilities

• Design and execute laboratory experiments and analyze data that may affect decisions regarding future patient care.
• Research and improve current methods and evaluate innovative techniques; perform regular quality and reproducibility checks.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.

Skills

Molecular biology

Mouse handling

Mucosal immunology

Bioinformatics

Gnotobiotics

Education

PhD/MD or equivalent

Job description

Primary Location Location S Department Immunobiology Shift Day (United States of America) Schedule Full time Weekly Hours 40 FTE 1 Employee Status Regular The Alenghat lab has an opening for a highly motivated, creative postdoctoral scientist with an interest in epigenetics, host-microbe interactions, and the intestine. We are studying interactions with the microbiota and molecular pathways that regulate how intestinal microbes impact mucosal and metabolic homeostasis, and chronic diseases such as inflammatory bowel disease. Recent Ph.D. candidates who are curious and passionate about scientific discovery and have expertise in molecular biology, mouse handling, and intestinal physiology/mucosal immunology are encouraged to apply. Experience with bioinformatics and/or gnotobiotics is also desirable.

MAJOR DUTIES AND RESPONSIBILITIES

• Develop the skills and knowledge (critical thinking and analysis of data, devising specific aims, long-term project planning and experimental design) to become an independent scientist
• Design, execute, and record laboratory experiments, and analyze data, which may affect decisions regarding future patient care.
• Research and improve current methods and evaluate innovative techniques.
• protocol and assay accuracy by conducting regular quality and reproducibility checks.
• Implement this knowledge in the Division/Department.
• Troubleshoot and correct erroneous results or problems with laboratory equipment.
• Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis.
• Present research at laboratory meetings, journal clubs, seminars, and meetings.
• Develop skills to critically review and discuss data being presented.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
• Progressively increasing responsibilities with mentorship of research staff and fiscal administration
• Maintain currency in field through continuing education, literature, and seminars.
• Be an active participant in the process through intellectual discussions with PI and other faculty, trainees and research staff.
• Solicit feedback on career trajectory from PI, mentoring committee and others who can provide coaching and insight.
• Attend required Cincinnati Children’s training sessions and ensure regulatory compliance with all institutional (i.e. Infection Control, ORCRA and others as applicable) policies and procedures.
• Perform other duties as assigned.
• Required: PhD/MD or equivalent

About Us

About Us At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.

Cincinnati Children's is recognized by U.S. News & World Report as atop 10 best Children's Hospitals in the nation for more than 15 years Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH)Funding Recognized as one of America’s Best Large Employers (2025), America’s Best Employers for New Grads (2025) One of the nation'sAmerica’s Most Innovative Companiesas noted by Fortune Consistently certified as great place to work A Leading Disability Employeras noted by theNational Organization on Disability Magnet® designated for the fourth consecutive time by theAmerican Nurses Credentialing Center (ANCC) We Embrace Innovation—Together. We believe in empowering our teams with the tools that help us work smarter and care better. That’s why we support the responsible use of artificial intelligence. By encouraging innovation, we’re creating space for new ideas, better outcomes, and a stronger future—for all of us.

Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status.

EEO/Veteran/Disability Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status.