Postdoctoral Research Associate - Oncology

CHEManager International; Memphis (TN); On-site; USD 52,000 - 70,000; Full time

Benefits offered by this job

Professional Development Allowance

Job summary

St. Jude Children’s Research Hospital in Memphis, TN invites applications for a postdoctoral fellowship in the Division of Molecular Oncology under Dr. Charles Roberts.

The research centers on SWI/SNF (BAF) chromatin remodeling complexes and cancer epigenetics, seeking mechanisms and vulnerabilities that drive cancer and identify novel therapies. Strong mentorship and extensive training opportunities are offered. Applicants should have recently earned a Ph.D.

Qualifications

• Ph.D. in molecular biology or related field.
• Peer-reviewed publications in relevant fields.

Skills

Molecular biology

Genetics/epigenetics

Cell biology

Cancer biology

Education

Ph.D. in molecular biology or related field

Job description

Job Description

We are excited to announce a postdoctoral fellowship available in the laboratory of Dr. Charles Roberts in the Division of Molecular Oncology at St. Jude Children's Research Hospital in Memphis, TN. Dr. Roberts is a leader in the field of cancer epigenetics, and his research has provided new insights into the central role of chromatin remodeling perturbations in cancer, discoveries that have been translated into investigational therapies for both pediatric and adult cancer patients. His research specifically focuses on SWI/SNF (BAF) chromatin remodeling complexes. Perturbation of these complexes has broad relevance to cancer as at least nine genes that encode SWI/SNF subunits are collectively mutated in over 20% of all cancers, making this the most frequently mutated chromatin regulator in human malignancies. Research in the Roberts laboratory is designed to discover the mechanisms by which SWI/SNF complexes regulate chromatin and transcriptional control and lineage specification, and the mechanisms by which mutation of SWI/SNF subunits drive cancer formation. We also seek to identify specific vulnerabilities that are conferred by SWI/SNF mutation with the goal of identifying novel therapeutic opportunities.

Location

Memphis, TN

Category

Postdoc

Department

Oncology

Shift

Weekday Day

Position Type

Full Time

Scheduled Weekly Hours

40

Req #

JR7765

Job Description

We are excited to announce a postdoctoral fellowship available in the laboratory of Dr. Charles Roberts in the Division of Molecular Oncology at St. Jude Children's Research Hospital in Memphis, TN. Dr. Roberts is a leader in the field of cancer epigenetics, and his research has provided new insights into the central role of chromatin remodeling perturbations in cancer, discoveries that have been translated into investigational therapies for both pediatric and adult cancer patients. His research specifically focuses on SWI/SNF (BAF) chromatin remodeling complexes. Perturbation of these complexes has broad relevance to cancer as at least nine genes that encode SWI/SNF subunits are collectively mutated in over 20% of all cancers, making this the most frequently mutated chromatin regulator in human malignancies. Research in the Roberts laboratory is designed to discover the mechanisms by which SWI/SNF complexes regulate chromatin and transcriptional control and lineage specification, and the mechanisms by which mutation of SWI/SNF subunits drive cancer formation. We also seek to identify specific vulnerabilities that are conferred by SWI/SNF mutation with the goal of identifying novel therapeutic opportunities.
Dr. Roberts' research is highly regarded and he has been elected as a fellow of the Academy of the American Association of Clinical Research, to the Society for Pediatric Research, the American Pediatric Society, and American Association of Physicians. He is a passionate mentor and is fully committed to training the next generation of scientists. Dr. Roberts leads a very successful, well-funded team with postdoctoral scientists, graduate students, technologists, senior scientists, and dedicated bioinformaticians. He additionally directs the NCI St. Jude Comprehensive Cancer Center, and in 2027 will relinquish this role to become president and CEO of St. Jude Children's Research Hospital. You will receive outstanding training in the development of scientific thinking and other skills such as grant writing, manuscript writing, and effective presentation, as well as have the freedom to develop your own ideas in a rigorous and supportive environment. Previous postdocs and graduate student trainees have successfully pursued careers as leaders in academia and industry. A list of previous trainees is available upon request.
The Division of Molecular Oncology and the top-notch core resources at St. Jude Children's Research Hospital will allow you access to the world-class expertise and technology necessary to perform high level science. In addition, postdoctoral fellows at St. Jude receive a generous yearly Professional Development Allowance for travel to scientific meetings.
Minimum Education: Candidates should have recently earned/expect to earn a Ph.D., have published in peer-reviewed journals, and have a
strong background in molecular biology, genetics/epigenetics, cell biology, and/or cancer biology.
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St. Jude is an Equal Opportunity Employer

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