Postdoctoral Research Associate - Immunology

ALSAC; Memphis (TN); On-site; USD 55,000 - 70,000; Full time

Job summary

The St. Jude Children’s Research Hospital in Memphis invites applications for a postdoctoral position in the Feng Laboratory, focusing on T-cell regulation and regulatory T cell identity.

The successful candidate will explore gene-regulatory networks governing Foxp3-dependent programs and immune modulation with translational potential. The role offers collaboration with cutting-edge core facilities and the chance to integrate mouse genetics, human T-cell biology, genomics, and synthetic

Qualifications

• Ph.D. in immunology, T-cell biology, molecular biology, biochemistry, cancer biology, or related field.
• Strong background in T-cell biology and gene regulation is preferred.
• Candidates with expertise in computational biology or bioinformatics are encouraged to apply.

Responsibilities

• Investigate how Treg cells regulate autoimmune inflammation and immune responses.
• Develop synthetic and engineering-based approaches to control T-cell function.
• Collaborate across disciplines using genetics, genomics, and protein biochemistry.

Skills

Immunology

T-cell biology

Molecular biology

Biochemistry

Cancer biology

Cell biology

Developmental biology

Computational biology

Bioinformatics

Education

Ph.D. in Immunology or related field

Job description

A postdoctoral position is available in the laboratory of Dr. Yongqiang (Yong) Feng in the Department of Immunology at St. Jude Children’s Research Hospital www.stjude.org/feng.

The Feng laboratory investigates the molecular and cellular mechanisms that govern T-cell fate, immune tolerance, and disease-associated immune responses. Our research focuses on how gene-regulatory networks and Foxp3-dependent programs establish, maintain, and destabilize regulatory T (Treg) cell identity and function, and how these pathways can be harnessed to modulate immunity in disease.

The successful candidate will investigate how Treg cells regulate autoimmune inflammation, tissue stress responses, age-associated immune dysregulation, and anti-tumor immunity. In addition, the candidate will participate in developing synthetic and engineering-based approaches to precisely control and reprogram T-cell function for both basic and translational investigation. Research projects are supported by multiple NIH grants and span fundamental and translational immunology.

The laboratory combines cutting-edge approaches in mouse genetics, human T-cell biology, molecular biology, protein biochemistry, functional immunology, genomics, and synthetic immunology to uncover mechanisms of immune regulation and translate discoveries into innovative strategies for immune modulation. Current projects provide outstanding opportunities to address fundamental questions in T-cell biology while developing expertise across multiple disciplines.

St. Jude Children’s Research Hospital offers exceptional institutional support, state-of-the-art core facilities, and a highly collaborative scientific environment. Together, these resources provide an outstanding training platform for the next generation of immunologists. Trainees will gain broad experience in gene regulation, immune-cell function, disease pathogenesis, cancer immunology, systems biology, and synthetic approaches to immune engineering.

Highly motivated recent Ph.D. graduates, or candidates with equivalent research experience, in immunology, T-cell biology, molecular biology, biochemistry, cancer biology, cell biology, developmental biology, computational biology, bioinformatics, or related fields are encouraged to apply.

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St. Jude is an Equal Opportunity Employer