Postdoctoral Research Associate - Developmental Neurobiology

St. Jude Children's Research Hospital; Memphis (TN); Presencial; USD 52.000 - 76.000; Jornada completa

Descripción de la vacante

St. Jude Children’s Research Hospital in Memphis, TN seeks a Postdoctoral Research Associate in Developmental Neurobiology to study neural circuit mechanisms of schizophrenia.

The role involves in vivo 2‑photon imaging of neuronal activity in rodent models, data analysis, and collaboration with a multidisciplinary team to advance our understanding of high‑risk genetic factors. The candidate should have a PhD in neuroscience or related field, hands-on 2‑photon imaging experience, and strong

Formación

• PhD in neuroscience or related field.
• DeepLabCut or similar methods experience.
• Demonstrated hands-on experience with 2-photon imaging techniques.
• Experience analyzing time-series data, preferably neuroimaging or behavioral studies.
• Excellent communication skills and ability to work in a collaborative environment.

Responsabilidades

• Conduct experiments to understand neural circuit mechanisms of schizophrenia.
• Perform in vivo imaging in behaving animals and analyze neural activity data.
• Collaborate with a diverse team and contribute to an interdisciplinary research program.

Conocimientos

2-photon imaging

Time-series data analysis

Computational neuroscience

Communication skills

Team collaboration

Educación

PhD in neuroscience or related field

Herramientas

DeepLabCut

2-photon microscopy

In vivo imaging

Descripción del empleo

Postdoctoral Research Associate - Developmental Neurobiology

Location

Memphis, TN

Category

Postdoc

Department

Position Type

Full Time

Scheduled Weekly Hours

40

JR8071

Job Description

A postdoctoral position is available for a highly motivated individual interested in the neural circuit mechanisms of schizophrenia.

Our laboratory conducts behavioral and 2-photon laser-scanning microscopy imaging of neuronal activity in mutant mice, with a focus on models of high-risk genetic risks for schizophrenia.

Our laboratory conducts 2-photon laser-scanning microscopy imaging of neuronal activity in the auditory system of behaving mice and rats. The laboratory is equipped with Mini-2p (Thorlabs) for imaging neuronal activity in behaving animals, two 2-photon mesoscopes (Thorlabs) for imaging large cortical and subcortical areas in awake head-fixed animals, two 2-photon microscopes for single-cell electrophysiological experiments in brain slices (Chun et al, Science 2014; Blundon et. al. Science 2017; Davenport et al., Cell 2022; Bayazitov et al., Cell Reports 2024, Patton et al., Cell Reports 2024; Eom, et al, Nature Communications 2024).

Preference will be given to applicants who have received their Ph.D. degrees in neuroscience or related fields within the last 3 years and have experience in imaging in vivo. Skills in computational neuroscience and data mining using machine learning methods are a plus.

Qualifications:

• PhD in neuroscience, or related fields
• DeepLabCut or similar methods
• Demonstrated hands-on experience with 2-photon imaging techniques
• Experience analyzing time-series data, preferably from neuroimaging or behavioral studies
• Excellent communication skills and ability to work in a collaborative environment

The successful candidate will join a diverse team of researchers whose efforts are directed toward understanding behavior at the levels of neural circuits, individual neurons, synapses, and molecules. The laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including an integrated support structure for rodent behavior testing, brain organoids, in vivo and ex vivo cellular imaging, bioinformatics, production of genetically engineered animal models, single-cell profiling, and advanced image processing and analysis. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies.

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