Postdoctoral Fellow - Genome Editing in HSPCs

Versiti Blood Research Institute; Elm Grove (WI); Vor Ort; USD 60.000 - 80.000; Vollzeit

Benefits dieser Stelle

Medical insurance

Dental insurance

Vision insurance

Paid time off

Holidays

Short- and long-term disability

Life insurance

401(k) matching

Voluntary programs

Discount programs

Zusammenfassung

The Versiti Blood Research Institute is seeking a postdoctoral fellow to explore the biology of human hematopoietic stem and progenitor cells (HSPCs), focusing on responses to genome changes and maintenance of function.

The program examines therapeutic genome editing in HSPCs, DNA damage responses, and cell-cycle regulation using primary CD34+ cells and related models. The fellow will lead projects and contribute to publications.

Qualifikationen

• Ph.D. in cell biology, molecular biology, genetics, hematology, stem cell biology, or a related field.
• Strong background in mitosis, chromosome biology, DNA damage responses, or cell-cycle regulation.
• Demonstrated ability to design and carry out independent research.
• Peer-reviewed publications.
• Experience with molecular and cellular biology techniques and quantitative analysis.
• Strong written and oral communication skills.

Aufgaben

• Design and conduct hypothesis-driven research in human HSPCs and related model systems.
• Investigate mechanisms of cell-cycle regulation, DNA damage responses, mitotic signaling, and chromosome integrity.
• Use molecular biology, genome editing, flow cytometry, and fluorescence microscopy to address biological questions.
• Analyze and interpret experimental results and develop follow-up studies.
• Prepare manuscripts and present research at scientific meetings.
• Participate in collaborative projects and contribute to the training of junior laboratory members.

Kenntnisse

Cell biology

Molecular biology

Genetics

Hematology

Stem cell biology

Ausbildung

Ph.D. in cell/molecular biology, genetics, hematology, or stem cell biology

Tools

Flow cytometry

Fluorescence microscopy

Live-cell imaging

CRISPR genome editing

Jobbeschreibung

The Versiti Blood Research Institute is seeking a postdoctoral fellow to explore the biology of human hematopoietic stem and progenitor cells (HSPCs), focusing on responses to genome changes and maintenance of function.

The program examines therapeutic genome editing in HSPCs, DNA damage responses, and cell-cycle regulation using primary CD34+ cells and related models. The fellow will lead projects and contribute to publications.