Postdoctoral Fellow- Dr. Miller

University of Alabama at Birmingham; Birmingham (AL); On-site; USD 52,000 - 70,000; Full time

Job summary

The University of Alabama at Birmingham invites applications for a postdoctoral position in the Miller lab, Department of Pathology, to develop and apply cutting-edge bioinformatics approaches addressing malignant brain tumors.

The fellow will analyze multiomic datasets, including bulk and single-cell RNA-seq, epigenomics, and proteomics, collaborating with pathology, neuro-oncology, neurosurgery, and genomics experts across the O'Neal Comprehensive Cancer Center resources.

Qualifications

• PhD, MD/PhD, or equivalent doctoral degree in Bioinformatics, Computational Biology, Genomics, Systems Biology, Computer Science, or a related field.
• Demonstrated experience with next-generation sequencing data analysis.
• Proficiency in R, Python, and related computational languages.
• Experience working in Linux and high-performance computing environments.
• Experience with agentic coding practices.
• Strong quantitative, analytical, and problem-solving skills.
• Excellent written and verbal communication skills.

Skills

Next-generation sequencing data

R

Python

Linux HPC

Agentic coding practices

Quantitative analysis

Written and verbal communication

Education

PhD/MD-PhD or equivalent

Job description

Please see Special Instructions for more details.

A postdoctoral position is available in the laboratory of C. Ryan Miller in the Department of Pathology at the University of Alabama at Birmingham ( UAB ). We seek a highly motivated computational scientist to develop and apply cutting-edge bioinformatics approaches to understand the molecular drivers of malignant brain tumors and identify new therapeutic opportunities.

The successful candidate will join a collaborative and multidisciplinary research environment focused on gliomas and other central nervous system tumors. The fellow will work closely with investigators in pathology, neuro-oncology, neurosurgery, cancer biology, genomics, proteomics, and computational biology, with access to extensive patient-derived datasets, state-of-the-art molecular profiling technologies, and the O'Neal Comprehensive Cancer Center's resources.

Research projects will involve integrative analysis of large-scale multiomic datasets generated from human tumors and experimental models, including bulk and single-cell transcriptomics, epigenomics, proteomics, and emerging spatial technologies.

The position provides outstanding opportunities for scientific independence, high-impact publications, grant development, and career advancement in cancer genomics and computational biology.

Required Qualifications

• PhD, MD/PhD, or equivalent doctoral degree in Bioinformatics, Computational Biology, Genomics, Systems Biology, Computer Science, or a related field.
• Demonstrated experience with next-generation sequencing data analysis.
• Proficiency in R, Python, and related computational languages.
• Experience working in Linux and high-performance computing environments.
• Experience with agentic coding practices.
• Strong quantitative, analytical, and problem-solving skills.
• Excellent written and verbal communication skills.

Preferred Qualifications

• Experience analyzing bulk RNA-seq and single-cell RNA-seq datasets.
• Experience with epigenomic data analysis, including CUT & RUN, ChIP-seq, ATAC-seq, chromatin accessibility, or DNA methylation profiling.
• Experience with proteomics data analysis, including mass spectrometry-based and non-mass spectrometry-based platforms.
• Familiarity with multiomic data integration, machine learning, statistical genetics, or network biology approaches.
• Knowledge of cancer biology, neuro-oncology, tumor evolution, or tumor microenvironment biology.
• Experience utilizing public genomic and proteomic resources such as TCGA, CPTAC, GEO, Synapse, and cBioPortal.
• Evidence of scientific productivity through peer-reviewed publications.

Posting Number: PF1093P

Open Date: 08/19/2026

Open Until Filled: Yes

UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, religion, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.

About University of Alabama at Birmingham

The University of Alabama at Birmingham

1720 2nd Ave South
Birmingham, AL 35294
Main Switchboard: [phone]
Hearing Impaired/TDD: [phone]

Supplemental Questions

• * Did you complete postdoctoral training at another institution? Please provide name of institution and duration of tenure (e.g., month/year-month/year). (Open Ended Question)
• * Did you complete postdoctoral training at UAB in Birmingham? Please provide duration of tenure (e.g., month/year-month/year). (Open Ended Question)