Postdoctoral Associate

ACS; California, Northern (MO, KY); Hybrid; USD 60,000 - 70,000; Full time

Job summary

Sanford Burnham Prebys Medical Discovery Institute invites applications for a Postdoctoral Fellow to join the Feng Laboratory. The role centers on determining structures of membrane proteins using cryo-EM and applying biochemical/biophysical methods to study function and structure–function relationships.

The position offers access to state-of-the-art facilities and strong opportunities for interdisciplinary collaboration and scientific growth, with a deadline of Nov. 16, 2026.

Qualifications

• PhD in biochemistry, biophysics, structural biology, or related field.
• Experience with cryo-EM is essential.
• Strong publication record and collaboration skills.

Responsibilities

• Employ cutting-edge cryo-EM to determine high-resolution structures of membrane proteins and protein complexes.
• Apply biochemical and biophysical approaches to investigate protein function and structure–function relationships.
• Collaborate within a multidisciplinary environment and engage in professional development and publications.

Skills

Cryo-EM

Biochemical techniques

Biophysical techniques

Protein expression

Education

PhD in biochemistry/biophysics/structural biology

Tools

Titan Krios/K3

Tecnai T12

Job description

The Feng Laboratory at Sanford Burnham Prebys Medical Discovery Institute invites applications for a highly motivated and passionate Postdoctoral Fellow to join our research team. Our laboratory is dedicated to uncovering the structural and functional mechanisms of disease-related membrane proteins and protein complexes, with a particular focus on endogenous ion channels. In this role, the Postdoctoral Fellow will: Employ cutting-edge cryo-electron microscopy (cryo-EM) to determine high-resolution structures of membrane proteins and protein complexes. Apply a broad range of biochemical and biophysical approaches to investigate protein function and elucidate structure-function relationships. The successful candidate will become an integral member of a collaborative and supportive research environment, with extensive opportunities for professional development, interdisciplinary collaboration, and scientific growth. Researchers have access to state-of-the-art core facilities on campus, including cryo-EM instrumentation (Titan Krios/K3 and Tecnai T12), biophysics facilities, protein expression and purification resources, and other advanced research infrastructure. This is a fully funded position that offers an excellent opportunity to pursue sustained, high-impact research, develop expertise in structural and functional biology, and generate strong publications.

Application deadline: Nov. 16, 2026

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