Postdoc: Retinal Genomics & Usher Syndrome Therapeutics

Mass General Brigham; Boston (MA); On-site; USD 72,000 - 74,000; Full time

Job summary

Mass General Brigham is seeking a highly motivated postdoctoral fellow to lead a collaborative retinal biology program tied to Usher syndrome research. The role involves integrating published and new data across human retina, organoids, and animal models, and coordinating across Mass Eye and Ear, Harvard-affiliated centers, and international collaborators.

The successful candidate will develop experimental strategies, perform advanced data analyses in R/Python, and contribute to peer-reviewed

Qualifications

• Doctorate in neuroscience, vision science, molecular biology, genetics, bioinformatics, or related field.
• Experience in retinal biology or transcriptomic analysis is desirable.
• Proficient in statistical software and data analysis.
• Strong written and verbal communication and ability to work independently.
• Experience with collaborative, multi-lab projects is preferred.

Responsibilities

• Integrate and critically evaluate retinal gene-expression and transcript data from multiple laboratories and experimental systems.
• Analyze single-cell and bulk transcriptomic datasets with attention to cell-type-specific expression and isoform usage.
• Compare findings across human retina, organoids, and animal models to determine best models for therapeutic insight.
• Design targeted validation experiments with collaborating labs, including RNAscope or immunofluorescence studies.
• Coordinate data exchange and maintain an integrated record of results across the collaboration.
• Present findings to collaborators and help establish project milestones and priorities.

Skills

Statistical analysis

Written communication

Verbal communication

Independent work

Team collaboration

Education

PhD or MD/PhD

Tools

R

Python

RNAscope

Immunofluorescence

Confocal microscopy

Job description

Mass General Brigham is seeking a highly motivated postdoctoral fellow to lead a collaborative retinal biology program tied to Usher syndrome research. The role involves integrating published and new data across human retina, organoids, and animal models, and coordinating across Mass Eye and Ear, Harvard-affiliated centers, and international collaborators.

The successful candidate will develop experimental strategies, perform advanced data analyses in R/Python, and contribute to peer-reviewed