Postdoc position in cellular senescence, reprogramming, and aging

scBiomarkers UTechS - Institut Pasteur; Indiana (PA); On-site; USD 46,000 - 55,000; Full time

Benefits offered by this job

Mentorship and career development

Access to cutting-edge facilities

Collaborative international team

Job summary

scBiomarkers UTechS - Institut Pasteur invites a postdoctoral fellow to study how senescent cells shape tissue function in vivo, focusing on plasticity, immune–stromal interactions, and remodeling in aging.

The position involves working with genetic mouse models, senolytics approaches, organoids, and single-cell profiling, in a highly collaborative international setting.

Candidates should have a PhD in a relevant field and a strong publication record, with proficiency in English.

Qualifications

• PhD in immunology, cell/molecular biology, aging biology or related field.
• Strong publication record in peer-reviewed journals.
• Experience with immunology and bioinformatic analysis (e.g., scRNA-seq) highly desirable.
• Skills in in vivo models are an advantage.

Responsibilities

• Investigate how senescent cells shape tissue function in vivo and influence tissue remodeling.
• Study interplay between senescence, plasticity, and immune-stromal interactions.
• Collaborate in an international team and contribute to high-impact publications.

Skills

Immunology

Cell biology

Bioinformatics

In vivo models

English proficiency

Education

PhD in immunology or related field

Job description

Application Deadline

30
Nov 2026

Position

Our laboratory is recruiting a postdoctoral fellow to investigate how senescent cells shape tissue function in vivo, particularly its interplay with cellular plasticity/reprogramming, immune–stromal interactions, and tissue remodeling, including in physiological contexts such as female reproductive biology and aging. "25-28 rue du Dr. Roux, 75015, Paris"

Host Lab

Our lab addresses a central question in biology: what is the physiological function of cellular senescence, and how does it transition from a regenerative program to a driver of pathology? We investigate how senescent cells control tissue plasticity and microenvironmental dynamics during regeneration, aging, and cancer, and how these processes can be modulated. Our research is primarily conducted in vivo. We combine genetic mouse models (lineage tracing, conditional perturbations), pharmacological interventions (senolytics and senomorphics), and organoid systems with functional assays, flow cytometry, advanced imaging, and high-dimensional approaches, including single-cell and spatial transcriptomics and epigenomics.

Candidate profiles

We Are Seeking Highly Motivated Candidates With

• A PhD (or near completion) in immunology, cell/molecular biology, female physiology, aging biology, or related fields.
• A strong track record of research and publications.
• Experience with immunology and bioinformatic analysis (e.g., scRNA‑seq) (highly desirable).
• Skills in in vivo models are an advantage.
• Ability to work independently and collaboratively within a diverse, international team.
• Proficiency in English (working language).

What We Offer

• A research program linking senescence, tissue repair, tumorigenesis, and aging
• A collaborative, international, and supportive lab culture.
• Access to cutting-edge facilities and interdisciplinary collaborations.
• Mentorship and career development support, including networking and grant‑writing opportunities.

Funding is available to start immediately but candidate will be encouraged and supported to apply for independent competitive grants.