Postdoc: Cracking Pediatric Cancer Dependencies

St Jude Children's Research Hospital; Memphis (TN); On-site; USD 55,000 - 75,000; Full time

Job summary

St. Jude Children's Research Hospital in Memphis is seeking a postdoctoral research associate to investigate molecular mechanisms that create therapeutic vulnerabilities in pediatric cancers.

The fellow will lead an independent project, combining genetic perturbation with epigenomic and transcriptomic profiling, protein interaction studies, and functional analysis in cancer models. The ideal candidate will have a strong background in cancer biology, molecular biology, genetics, or gene

Qualifications

• PhD or equivalent doctoral degree in a relevant field.
• Experience with cancer biology, molecular biology, genetics, or gene regulation.
• Working understanding of CRISPR-based screening and its interpretation.
• Interest in using genomic/epigenomic data to build and test mechanistic hypotheses.

Responsibilities

• Lead an independent project from a cancer dependency to a mechanistic explanation.
• Design decisive experiments and follow unexpected results.
• Perform genetic perturbation coupled with epigenomic/transcriptomic profiling and protein interaction studies.
• Work to determine why a dependency exists and how it can be exploited for treatment.

Skills

Molecular biology

Genetics

Cancer biology

CRISPR-based screening

Experimental design

Independence

Data interpretation

Education

PhD or equivalent doctoral degree

Tools

CRISPR screening

Epigenomic profiling

Transcriptomic profiling

Job description

St. Jude Children's Research Hospital in Memphis is seeking a postdoctoral research associate to investigate molecular mechanisms that create therapeutic vulnerabilities in pediatric cancers.

The fellow will lead an independent project, combining genetic perturbation with epigenomic and transcriptomic profiling, protein interaction studies, and functional analysis in cancer models. The ideal candidate will have a strong background in cancer biology, molecular biology, genetics, or gene