Postdoc: Breast Cancer Initiation & Mammary Biology

St. Jude Children's Research Hospital, Inc.; Memphis (TN); On-site; USD 65,000 - 90,000; Full time

Job summary

The dos Santos Laboratory at St. Jude Children’s Research Hospital seeks a highly motivated postdoctoral research associate to study cellular and molecular regulators of mammary gland biology and breast cancer susceptibility.

The successful candidate will lead an independent, collaborative project using mouse models, organoids, and single-cell technologies in a multidisciplinary setting. Applicants should hold a PhD/MD/MD-PhD in a relevant field and demonstrate a strong publication record,

Qualifications

• PhD, MD, MD/PhD or equivalent doctoral degree in cancer biology, molecular biology, cell biology, developmental biology, genetics, immunology, bioengineering, computational biology, or a related discipline.
• Strong record of scientific productivity and evidence of independent research ability.
• Experience with at least one of the following: mouse models, organoid culture, molecular and cellular biology, microscopy, flow cytometry, single-cell genomics, epigenomics, or computational analysis.
• Strong quantitative, organizational, written, and oral communication skills.
• Ability to work independently while contributing effectively to collaborative projects.
• Commitment to rigorous, reproducible, and ethical research.
• Applicants with complementary expertise in immunology, stromal biology, developmental biology, aging, metabolism, bioengineering, or computational genomics are strongly encouraged to apply.

Responsibilities

• Design, conduct, analyze, and interpret independent research projects.
• Use genetically engineered mouse models, mammary transplantation assays, organoid systems, and mammalian cell culture.
• Perform molecular, cellular, imaging, and functional assays relevant to mammary gland and cancer biology.
• Collaborate with computational scientists to analyze single-cell RNA-seq, ATAC-seq, spatial, and other genomic datasets.
• Maintain rigorous and reproducible experimental records.
• Present findings at laboratory meetings, institutional seminars, and national or international conferences.
• Prepare manuscripts, fellowship applications, and research proposals.
• Mentor graduate students, research staff, and other junior laboratory members.
• Contribute to a rigorous, collaborative, inclusive, and intellectually engaging laboratory environment.

Skills

Mouse models

Organoid culture

Single-cell genomics

Molecular biology

Imaging

Flow cytometry

Computational analysis

Education

PhD, MD, MD/PhD or equivalent doctoral degree

Tools

Single-cell RNA-seq

Organoid culture

Mammalian cell culture

Microscopy

Flow cytometry

Spatial genomics

Job description

The dos Santos Laboratory at St. Jude Children’s Research Hospital seeks a highly motivated postdoctoral research associate to study cellular and molecular regulators of mammary gland biology and breast cancer susceptibility.

The successful candidate will lead an independent, collaborative project using mouse models, organoids, and single-cell technologies in a multidisciplinary setting. Applicants should hold a PhD/MD/MD-PhD in a relevant field and demonstrate a strong publication record,