Post Doctoral Scientist - Cancer/Epigenetics/Bioinformatics/Nucleic Acid Metabolism

Nationwide Children's Hospital; Columbus (OH); Sur place; USD 55 000 - 70 000; Plein temps

Résumé du poste

Nationwide Children's Hospital's Center for Childhood Cancer Research in Columbus, OH, seeks a postdoctoral researcher to lead investigations into the biology of R-loops in Ewing sarcoma. The role involves mechanistic studies using molecular biology, genomics, single-cell analyses, and microscopy, with collaboration across NCH and The Ohio State University.

The successful candidate will design experiments, analyze data, and present findings under mentorship, with appointment up to seven years

Qualifications

• PhD or equivalent degree in a relevant science field.
• Experience conducting research during PhD program.

Responsabilités

• Designs experiments, develops protocols, and conducts research under a faculty mentor.
• Trains and supervises technical staff to perform essential techniques.
• Records and analyzes data; develops hypotheses for further study.
• Prepares scientific papers and presents findings at conferences.
• Collaborates with other ongoing research efforts at NCH or OSU.
• Works toward research independence and seeks external funding opportunities.

Connaissances

Interpersonal skills

Lab techniques

Computer skills

Qualitative methods

Quantitative methods

Project management

Formation

PhD or equivalent

Description du poste

Overview:

This position is in the Center for Childhood Cancer Research in Dr. Alex Bishop’s lab. Our team is focused on understanding the underlying biology that is dysregulated in Ewing sarcoma with the long-term goal of identifying therapeutic vulnerabilities. The postdoc is expected to take a lead role in a project investigating the biology of R-loops in Ewing sarcoma (mechanistic regulation, modulation, dependency programs and targeting)using molecular cell biology, genomics, single cell and microscopic techniques. Experience in some or all of these areas is desirable. Motivation and interest to drive and develop the project is critical for success as is a willingness to participate in a collaborative environment.

Job Description Summary:

Conducts research, designs experiments, analyzes data, and presents findings under the mentorship of an established RI principal investigator or Senior Research Scientists. Appointment is a maximum of 7 years in length.

Job Description:

Essential Functions:

• Designs experiments, develops protocols, and conducts research under the guidance of a faculty mentor.
• Assists in the training and supervision of technical support staff in performing specific techniques essential to carrying out the research program.
• Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed.
• Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums.
• Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
• Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.

Education Requirement:

PhD or equivalent degree in relevant field of science, required.

Licensure Requirement:

(not specified)

Certifications:

(not specified)

Skills:

• Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
• Excellent laboratory technical skills.
• Excellent computer skills.
• Skills in qualitative and quantitative research methods.
• Ability to proactively manage and drive projects.

Experience:

Research experience from PhD program, required.

Physical Requirements:

OCCASIONALLY: Bend/twist, Climb stairs/ladder, Lifting / Carrying: 11-20 lbs

FREQUENTLY: Lifting / Carrying: 0-10 lbs, Standing, Walking

CONTINUOUSLY: Audible speech, Color vision, Computer skills, Decision Making, Depth perception, Flexing/extending of neck, Hand use: grasping, gripping, turning, Hearing acuity, Interpreting Data, Peripheral vision, Problem solving, Reaching above shoulder, Repetitive hand/arm use, Seeing – Far/near, Sitting, Squat/kneel

Additional Physical Requirements performed but not listed above:

Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines associated research and manuscript writing.

"The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet"