Post Doctoral Scientist - Cancer/Epigenetics/Bioinformatics/Nucleic Acid Metabolism

Nationwide Children's Hospital; Columbus (OH); On-site; USD 52,000 - 64,000; Full time

Job summary

Nationwide Children’s Hospital is seeking a postdoctoral researcher to lead experiments studying the biology of R-loops in Ewing sarcoma within the Center for Childhood Cancer Research. The role involves molecular biology, genomics, single-cell and imaging approaches, under PI guidance, with emphasis on independence and collaboration.

The ideal candidate has a PhD in a relevant field, strong wet-lab skills, and a demonstrated ability to design and interpret experiments.

Qualifications

• PhD in a relevant field required.
• Strong analytical and problem-solving skills.
• Experience designing and executing biological experiments.
• Ability to work independently and manage projects.
• Collaborative team player with good communication.

Responsibilities

• Designs experiments and protocols under supervision of PI or senior staff.
• Mentors/ trains technical staff for essential techniques.
• Records and analyzes data; develops hypotheses for further study.
• Prepares manuscripts and presents findings at meetings.
• Collaborates with other labs and seeks external funding opportunities.

Skills

Interpersonal skills

Lab techniques

Computer skills

Qualitative methods

Quantitative methods

Project management

Education

PhD or equivalent degree

Job description

Overview

This position is in the Center for Childhood Cancer Research in Dr. Alex Bishop’s lab. Our team is focused on understanding the underlying biology that is dysregulated in Ewing sarcoma with the long-term goal of identifying therapeutic vulnerabilities. The postdoc is expected to take a lead role in a project investigating the biology of R-loops in Ewing sarcoma (mechanistic regulation, modulation, dependency programs and targeting) using molecular cell biology, genomics, single cell and microscopic techniques. Experience in some or all of these areas is desirable. Motivation and interest to drive and develop the project is critical for success as is a willingness to participate in a collaborative environment.

Job Description Summary

Conducts research, designs experiments, analyzes data, and presents findings under the mentorship of an established RI principal investigator or Senior Research Scientists. Appointment is a maximum of 7 years in length.

Essential Functions

• Designs experiments, develops protocols, and conducts research under the guidance of a faculty mentor.
• Assists in the training and supervision of technical support staff in performing specific techniques essential to carrying out the research program.
• Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed.
• Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums.
• Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
• Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.

Education Requirement

PhD or equivalent degree in relevant field of science, required.

Licensure Requirement

(not specified)

Certifications

(not specified)

Skills

• Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
• Excellent laboratory technical skills.
• Excellent computer skills.
• Skills in qualitative and quantitative research methods.
• Ability to proactively manage and drive projects.

Experience

Research experience from PhD program, required.

Physical Requirements

OCCASIONALLY: Bend/twist, Climb stairs/ladder, Lifting / Carrying: 11-20 lbs
FREQUENTLY: Lifting / Carrying: 0-10 lbs, Standing, Walking
CONTINUOUSLY: Audible speech, Color vision, Computer skills, Decision Making, Depth perception, Flexing/extending of neck, Hand use: grasping, gripping, turning, Hearing acuity, Interpreting Data, Peripheral vision, Problem solving, Reaching above shoulder, Repetitive hand/arm use, Seeing - Far/near, Sitting, Squat/kneel

Additional Physical Requirements Performed But Not Listed Above

Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines associated research and manuscript writing.

EOE M/F/Disability/Vet