Post-Doctoral Research Fellow - Clurman Lab

Mundelein Elementary School District 75; Seattle (WA); On-site; USD 80,172 - 95,014; Full time

Benefits offered by this job

Medical benefits

Vision/Dental

Retirement plan

Paid time off

Sick leave

Holidays

Parental leave

Job summary

Fred Hutchinson Cancer Center in Seattle is seeking a highly qualified Post‑Doctoral Research Fellow to study molecular pathogenesis and therapeutic strategies targeting Wee1 and CDK4/6 in head and neck squamous cell cancer (HNSCC).

Primarily based in the Clurman lab, the role also enables collaboration with teams across Fred Hutch on machine‑learning‑enabled drug screening, mouse models and functional genomics.

Qualifications

• Broad expertise in cell and molecular biology methods and the ability to master new techniques and approaches.
• Experience with mouse models and xenografting is preferred.
• Experience in functional genomics and/or drug screening also preferred.
• Excellent written and oral communication skills.
• Record of productive and rigorous research, including at least one primary publication in an impactful peer‑reviewed journal.
• Ability to independently plan, conduct, and analyze research.

Responsibilities

• Study molecular pathogenesis and therapeutic strategies associated with Wee1 and CDK4/6 in head and neck squamous cell cancer (HNSCC).
• Collaborate with other Fred Hutch research groups within the HNSCC team, including ML-enabled drug screening, mouse models, and functional genomics.
• Perform high‑throughput functional genomics and drug screening and analyze gene expression in tissue culture cells.
• Work with murine cancer models and genomics/proteomics data.
• Independently plan and guide research projects within a collaborative lab environment.

Skills

Cell & molecular biology

Mouse models

Functional genomics

Communication skills

Publication record

Independent researcher

Education

PhD, MD, or MD/PhD

Job description

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Clurman lab (https://research.fredhutch.org/clurman/en.html) works at the intersection of two fields: cell cycle control and protein degradation by the ubiquitin‑proteasome system. Our work focuses on both tumorigenesis and normal biology, and our overall goal is to apply new mechanistic insights to understand cancer development and to develop new therapeutic strategies.

The Fred Hutch/University of Washington Head and Neck Research Program – Fred Hutch and the University of Washington have a world‑class program in Head and Neck Cancer that spans from clinical to translational to basic research. The program drives collaborative research among its members, and its unique assets include a surgical core that provides fresh tumor specimens and PDX models, novel engineered murine models, state‑of‑the‑art AI‑enabled drug screening in microtumors and cancer cells, and more.

Responsibilities

The Clurman lab is seeking a highly qualified and motivated Post‑Doctoral Research Fellow. The project will study molecular pathogenesis and therapeutic strategies associated with two promising cell cycle targets in head and neck squamous cell cancer (HNSCC), Wee1 and CDK4/6. Primarily based in the Clurman lab, this position also provides the opportunity to work collaboratively with other Fred Hutch research groups within the HNSCC team, including Taran Gujral (machine learning‑enabled drug screening), Slobodan Beronja (mouse models of HNSCC), and Patrick Paddison (functional genomics). This work will encompass a broad array of cell and molecular biology approaches, including high‑throughput functional genomics and drug screening, gene expression and analyses in tissue culture cells, murine models of cancer, and genomics/proteomics. We value lab members who are highly collaborative but can also independently develop and guide research projects.

Minimum Qualifications

• PhD, M.D., or M.D., Ph.D. (or equivalent degree) in cell and molecular biology, cancer biology, biochemistry, or a related field
• Broad expertise in cell and molecular biology methods and the ability to master new techniques and approaches
• Experience with mouse models and xenografting is preferred
• Experience in functional genomics and/or drug screening also preferred
• Excellent written and oral communication skills
• Record of productive and rigorous research, including at least one primary publication in an impactful peer‑reviewed journal
• Ability to independently plan, conduct, and analyze research.

The annual base salary range for this position is from $80,172 to $95,014, and pay offered will be based on experience and qualifications.

This position is not eligible for H‑1B sponsorship at this time.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well‑being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income‑based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).