Post Doctoral Fellow for Research Lab

Saint Louis University; St. Louis (MO); Sur place; USD 52 000 - 64 000; Plein temps

Résumé du poste

Saint Louis University invites applications for a postdoctoral fellow position focused on pediatric intestinal failure and related liver and gut signaling. The lab uses large animal models, organoid cultures, and multi-omics approaches to study intestinal adaptation, barrier function, and systemic disease processes.

The candidate will collaborate across departments with experience in cell culture, organoid systems, and molecular biology; responsibilities include data analysis, manuscript

Qualifications

• PhD/MD-equivalent in biology or related field required; strong background in gastrointestinal biology or related disciplines preferred.
• Experience with cell culture, organoid systems, molecular biology, and omics approaches is desirable.
• Strong communication skills and ability to work independently and collaboratively.

Responsabilités

• Plan and execute experiments, analyze data, and interpret results in a multidisciplinary team.
• Maintain accurate lab records and contribute to protocol development and quality control.
• Prepare figures and manuscripts; present findings at meetings and conferences; assist with grant progress reports.

Connaissances

Cell culture

Organoid systems

Molecular biology

Immunology

Histology

Transcriptomics

Metabolomics

Bioinformatics

Formation

PhD or MD or MD/PhD or DVM in biology/biomedical sciences

Outils

PCR

ELISA

Immunostaining

Description du poste

Who is Saint Louis University? Founded in 1818, Saint Louis University is one of the nation's oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.

A postdoctoral fellow research position is available, focused on pediatric intestinal failure, short bowel syndrome, parenteral nutrition associated injury, bile acid signaling, microbiome related mechanisms, epithelial biology, liver injury and other systemic processes and diseases. The successful candidate will join a multidisciplinary team studying how intestinal nutrient exposure, microbial metabolites, epithelial signaling, and gut and liver communication regulate intestinal adaptation, barrier function, inflammation, liver disease and other systemic processes and diseases.

The postdoctoral fellow will work across complementary experimental systems, including neonatal large animal models, intestinal epithelial organoid-derived cultures, liver organoid or liver-derived cell systems, human tissue-based studies, molecular and multi-omic assays and others.

Responsibilities

The postdoctoral fellow will participate in experimental planning, execution, data analysis, and interpretation. Responsibilities may include large animal sample collection and processing, epithelial organoid culture and functional assays, liver organoid or liver-derived cell assays, molecular biology, immunostaining, imaging, quantitative PCR, ELISA or multiplex assays, microbiome and metabolomic sample preparation, bile acid and short chain fatty acid related analyses, and integration of physiologic, histologic, molecular, omics datasets and tasks as required by the lab.

The post-doc will be expected to maintain accurate laboratory records, contribute to protocol development and quality control, prepare figures and manuscripts, present findings at laboratory meetings and scientific conferences, and assist with grant progress reports and future grant applications. The position requires close collaboration with investigators in pediatric gastroenterology, hepatology, pathology, microbiology, immunology, surgery, veterinary medicine, bioinformatics, core facilities, other departments, individuals and labs.

Qualifications

Applicants should have a PhD, MD, MD/PhD, DVM, or equivalent doctoral degree in a relevant field, including biology, physiology, molecular biology, microbiology, immunology, pathology, biomedical sciences, nutrition, or related disciplines. Experience with cell culture, organoid systems, molecular biology, animal models, gastrointestinal biology, liver biology, microbiome research, immunology, histology, transcriptomics, metabolomics, or bioinformatics is desirable. Prior experience with large animal models is helpful.

The ideal candidate will be highly motivated, organized, detail-oriented, and able to work both independently and collaboratively. Strong written and oral communication skills are important.

Function

Research Support

Scheduled Weekly Hours: 40

Saint Louis University is an equal opportunity/affirmative action employer. All qualified candidates will receive consideration for the position applied for without regard to race, color, religion, sex, age, national origin, disability, marital status, sexual orientation, military/veteran status, gender identity, or other non-merit factors. If accommodations are needed for completing the application and/or with the interviewing process, please contact Human Resources at 314-977-5847.