PLS Scientist III

RXinsider LTD.; Oakdale, Northern (MN, KY); Hybrid; USD 85,000 - 95,000; Full time

Benefits offered by this job

Medical insurance

Dental & Vision

401K retirement plan

Paid time off

Life insurance

Disability insurance

Tuition reimbursement

Employee assistance program

Job summary

Pace® Life Sciences delivers a comprehensive suite of contract CMC development, CTM manufacturing, regulatory compliance, consulting, and facility support services to the pharmaceutical, biopharmaceutical, and gene therapy industries.

Our Scientist III role conducts complex laboratory analyses in a GxP environment, develops and validates analytical methods, executes testing, and interprets data to support product development and quality control, onsite in Oakdale, MN.

Qualifications

• Bachelor's or Master's in Chemistry, Biochemistry, Pharmaceutical Sciences, or related field with 5–10 years in a GxP lab.
• Hands-on experience with HPLC, UPLC, GC and LC-MS in regulated environments.
• Strong knowledge of GLP/GMP/GxP regulations.
• Experience in method development, optimization, and validation is desirable.
• Proficient in data analysis and technical reporting.

Responsibilities

• Perform complex analytical testing including HPLC, GC, LC-MS, Dissolution, spectroscopy, and wet chemistry per SOPs and GxP.
• Develop, optimize, and validate analytical methods.
• Analyze data, troubleshoot issues, and report results clearly.
• Operate, maintain, and calibrate laboratory instruments and perform preventive maintenance.
• Document experiments thoroughly in notebooks and LIMS.
• Investigate OOS/OOT results and implement corrective actions.
• Contribute to SOPs, test methods, and validation protocols.
• Collaborate with project teams to meet timelines.
• Ensure compliance with safety, GxP, and quality policies.
• Provide training and mentorship as needed.

Skills

Analytical testing

Chromatography

Data analysis

Technical reporting

Team leadership

Problem solving

Microsoft Office

LIMS familiarity

Education

BSc/ MSc in Chemistry / Biochemistry / Pharmaceutical Sciences

Tools

LC-MS

HPLC/UPLC/GC

LIMS

Job description

Shift

Monday through Friday, 8:00 AM - 5:00 PM

Are you ready to work making the world a safer, healthier place? Join our mission to continuously move science forward; to innovate and advance all aspects of our business to improve the health and safety of our communities and lives.

This is a full-time, onsite, Scientist 3 position located in Oakdale, MN, Monday through Friday, 8:00 a.m. - 5:00 p.m.

Compensation: $85,000 - $95,000 per year

The salary for this position reflects a variety of factors. Compensation will be determined based on the candidate’s geographic location, relevant experience, education, skills, and alignment with internal equity. Market conditions, budgetary considerations, and organizational compensation guidelines may also influence the final offer.

Make an Impact. Build a Career.

Pace® Life Sciences delivers a comprehensive suite of contract CMC development, CTM manufacturing, regulatory compliance, consulting, and facility support services to the pharmaceutical, biopharmaceutical, and gene therapy industries. Operating across a network of CDMO sites, GMP analytical testing laboratories, and manufacturing support centers, we partner with clients to efficiently advance programs from early development through commercialization.

Our experienced industry experts and continued investment in state-of-the-art facilities reflect our commitment to quality, speed, and reliability. United by a shared purpose, we bring meaningful value to patients, healthcare professionals, and health businesses worldwide by delivering services that support a safer, healthier future.

Summary

The PLS Scientist III at Pace Analytical Life Sciences, LLC is responsible for performing a variety of complex laboratory analyses, studies, and method development activities in a GxP regulated environment. This role contributes to the development and validation of analytical methods, executes testing plans, and interprets data to support pharmaceutical and biopharmaceutical product development and quality control.

Job Responsibilities

• Execute complex analytical testing including but not limited to HPLC, GC, LC-MS, Dissolution, spectroscopy (UV/Vis, FTIR), and wet chemistry techniques, following established SOPs and GxP guidelines.
• Conduct method development, optimization, and validation activities for various analytical methods, ensuring suitability for intended purpose and compliance with regulatory requirements.
• Analyze and interpret data, troubleshoot analytical issues, and provide clear, concise reports and summaries of experimental results.
• Operate, maintain, and calibrate laboratory instrumentation, ensuring proper functioning and adherence to preventative maintenance schedules.
• Document all experimental procedures, observations, and results accurately and thoroughly in laboratory notebooks and LIMS systems.
• Participate in the investigation of out-of-specification (OOS) and out-of-trend (OOT) results, identifying root causes and implementing corrective actions.
• Contribute to the drafting and revision of Standard Operating Procedures (SOPs), test methods, and validation protocols.
• Work collaboratively with project teams, providing scientific expertise and supporting coordination to achieve project goals and timelines.
• Ensure compliance with all safety regulations, GxP standards, and internal quality policies.
• Provide training and mentorship to junior scientists and laboratory personnel as needed.

Job Qualifications

• Bachelor's or Master's degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related scientific field with 5-10 years of relevant experience in a GxP regulated laboratory environment;
• Proven hands‑on experience with a variety of analytical techniques, including advanced chromatography (HPLC, UPLC, GC) and mass spectrometry (LC-MS).
• Strong understanding of GxP (GLP/GMP) regulations and their application in a laboratory setting.
• Experience in analytical method development, optimization, and validation is highly desirable.
• Proficiency in data analysis, chromatographic interpretations, and technical report writing.
• Strong communication (written and verbal) and interpersonal skills, with the ability to work and lead effectively in a team environment.
• Familiarity with LIMS (Laboratory Information Management System) and other laboratory software.
• Excellent trouble‑shooting, problem‑solving skills and attention to detail.
• Ability to manage multiple projects concurrently and meet deadlines.
• Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint)
• Experience providing technical guidance, mentoring, or informal leadership is strongly preferred.

Physical/Mental Requirements

The physical demands described herein are representative of those that must be met by an employee to successfully perform the essential functions of the job. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.

Mobility to work in a lab and office setting, use standard office and lab equipment and stamina to sit for extended periods of time; exerting up to 20 pounds of force occasionally and/or up to 10 pounds of force frequently to lift, carry, push, pull or move objects; vision to read printed materials and computer screens; and hearing and speech to communicate in person or over the telephone.

Working Environment

Work is performed in a lab and office setting. Work is subject to chemicals, fumes, gases, noxious odors, and related items in a lab and sample setting.

Find Your Place at Pace - We need you - your curiosity, your talents, and your drive - to help us advance this important work.

Benefits

When you join Pace®, you commit to work that makes a positive impact on our communities and our world. We commit to supporting you with benefits and perks that make a positive impact on your life. Full-time roles are eligible for our comprehensive benefits program which includes competitive salaries, medical, dental vision, 401K retirement savings plan (100% vested immediately in the employer match), life, disability and voluntary benefits, paid time off for holiday, sick and vacation days, HSA, wellness program, flexible spending accounts, tuition reimbursement, Employee Assistance program, parental leave, optional legal coverage and ID theft.

• Full-time roles are eligible for our comprehensive benefits program which includes competitive salaries
• medical
• dental vision
• 401K retirement savings plan (100% vested immediately in the employer match)
• life
• disability and voluntary benefits
• paid time off for holiday
• sick and vacation days
• HSA
• wellness program
• flexible spending accounts
• tuition reimbursement
• Employee Assistance program
• parental leave
• optional legal coverage
• ID theft

Equal Opportunity Employer

Pace® provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, creed, color, religion, genetics, protected veteran status, national origin, sex, age, disability, marital status, sexual orientation, gender identity or expression, citizenship, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.