Pharmacometrician

ABBVIE; North Chicago (IL); On-site; USD 110,000 - 209,000; Full time

Job summary

AbbVie in the United States seeks a lead pharmacometrician to conceive and execute statistical and mathematical PK/PD models supporting Clinical Pharmacology and Pharmacometrics goals.

You will propose modeling ideas, lead analyses for Phase 1-4, and author regulatory documents; collaborate across functions and present at conferences. A PhD with extensive experience in data science and pharmacometrics is preferred.

Qualifications

• PhD or equivalent with extensive experience in data science, biostatistics, modeling and pharmacometrics.
• Excellent interpersonal and teamwork abilities.
• Ability to interact with internal and external groups.
• Proven scientific insight and strong technical skills.

Responsibilities

• Support Phase 1-4 studies with data analysis, modeling and simulation to guide study design and clinical pharmacology strategy.
• Author regulatory and scientific documents including analysis plans and reports.
• Conduct data analyses including non-compartmental analyses and literature data analyses.
• Collaborate with cross-functional teams to present and discuss findings.
• Publish scientific work and present at conferences.

Skills

PK/PD modeling

Data analysis

Modeling and simulation

Leadership competencies

Education

PhD or equivalent

Master’s Degree or equivalent

Bachelor’s Degree or equivalent

Job description

• Compensation: USD 109500 - USD 208500 - yearly

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com . Follow @abbvie onLinkedIn, Facebook ,Instagram ,X andYouTube.

Job Description

Conceive and execute statistical and mathematical models that achieve projects, Clinical Pharmacology and Pharmacometrics goals. Propose PK/PD modeling and simulation ideas and implement those efforts. Investigate, identify, develop, and optimize methods and techniques in the field of PK/PD modeling. Act as a lead pharmacometrician in his/her area of expertise and critically evaluate relevant Pharmacometric, PK/PD, Clinical Pharmacology and regulatory advances and integrate this knowledge into Clinical Pharmacology strategy for research or development programs

Responsibilities

Contribute to clinical development by supporting Phase 1-4 studies with data analysis, modeling and simulation evaluations to guide study design, and clinical pharmacology strategy.

• Author regulatory documents including analysis plans, study reports, population PK reports, exposure-response analyses reports, common technical documents, white papers, and other similar documents.
• Conduct data analyses including non-compartmental analyses, modeling and simulation, advanced analytics, as well as literature data analyses.
• Participate and present at various departmental and cross functional teams such as Clin Pharm meetings, Journal club.
• Collaborate with scientific support from other Clinical Pharmacology functional groups to provide a unified clinical pharmacology position to clinical, CMC and regulatory teams.
• Author scientific publications and present at scientific conferences

Qualifications

• PhD with 0 years of experience in a relevant field, Master’s Degree or equivalent education and typically 7+ years of experience, Bachelor’s Degree or equivalent education and typically 10+ years of experience;(*relevant field includes experience with data science, mathematics, biostatistics, modeling and simulation, Pharmacometrics or systems pharmacology)
• Excellent interpersonal skills
• Ability to interact externally and internally and perform in a team setting
• Demonstrates scientific acumen and has technical skills to perform the role
• Key Leadership Competencies:
  o Persistent and resilient finds the way to move good ideas forward
  o Uses mistakes, failure and reflection as vehicles for learning and improvement
  o Delivers business results while also positioning AbbVie for long-term success
  o Connects unrelated concepts, generates original or unique ideas
  o Influences colleagues to achieve cross-functional alignment

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.