Pharmacokinetics & Systems Biology AI Benchmark Designer

Obsidian; San Diego (CA); On-site; USD 120,000 - 180,000; Part time

Job summary

Obsidian is seeking a Computational Pharmacokinetics & Systems Biology Expert to design graduate-level computational problems using real scientific software. You will craft multi-step workflows, interpret simulation results, and guide AI models through research-grade tasks with a focus on strategic experimentation and data interpretation.

You will work with tools like libRoadRunner and Tellurium, applying SBML-based workflows, and will write code to set up problems, validators, and scripts for

Qualifications

• Graduate-level training in a relevant STEM field (MS, PhD, or equivalent research experience).
• Proven proficiency with at least one of the listed scientific software libraries, shown through publications, open-source contributions, or professional work.
• Strong Python skills — you'll be writing problem setups, oracle functions, and solution validators.
• Ability to work independently and refine problem designs based on feedback.
• Comfortable working in a Linux/terminal environment with remote compute sandboxes.
• Available for at least 15–20 hours per week.

Responsibilities

• Create graduate-level problems that require skilled use of specialized scientific software and multi-step workflows.
• Test problems against state-of-the-art AI models and refine until target difficulty is reached.
• Design problems where the AI plans queries or experiments to uncover information not directly visible.
• Work with libRoadRunner, Tellurium, or SBML-based tools for simulations and analysis.

Skills

Python programming

Problem design

Independent work

Linux/terminal

Education

MS/PhD in STEM

Tools

libRoadRunner

Tellurium

SBML tools

Job description

Obsidian is seeking a Computational Pharmacokinetics & Systems Biology Expert to design graduate-level computational problems using real scientific software. You will craft multi-step workflows, interpret simulation results, and guide AI models through research-grade tasks with a focus on strategic experimentation and data interpretation.

You will work with tools like libRoadRunner and Tellurium, applying SBML-based workflows, and will write code to set up problems, validators, and scripts for