Pharmacist

molecule.xyz; Germany (OH); On-site; USD 75,467 - 98,688; Full time

Job summary

molecule.xyz is seeking a Senior Individual Contributor for a unique role in formulating cognitive and performance compounds such as modafinil and peptides. The position involves designing formulations, ensuring strict adherence to documentation and GMP standards, and working independently.

Applicants should hold a relevant pharmacy license and have at least five years of formulation experience, including work with sterile injectables. Strong analytical skills and a commitment to high standards of accuracy and sterility are crucial.

Qualifications

• 5+ years of hands-on formulation experience in pharma.
• Deep knowledge of unit operations for encapsulation/tableting.
• Practical command of dissolution and stability study design.

Responsibilities

• Design oral solid-dose formulations from active properties.
• Own encapsulation, blending, and aseptic processing end to end.
• Write documentation that holds up.

Skills

Formulation experience

Knowledge of excipient functionality

Documentation rigor

Experience with sterile injectables

Problem-solving with actives

Understanding of GMP

Education

Approbation as Apotheker

Degree in pharmaceutics or equivalent

Tools

HPLC

Dissolution apparatus

Job description

Molecule and BIO.xyz are building the foundation of Decentralized Science (DeSci) — where biotech meets web3 to make scientific research community-owned, transparent, and faster to market.

Molecule provides the infrastructure to turn intellectual property (IP) into programmable, on‑chain assets through our IP‑NFT framework and evolving protocol stack. This enables researchers, patients, and communities to fund and govern biotech projects in new, open ways.

BIO.xyz is the coordination and economic layer of DeSci, powering BioDAOs through funding, governance, and ecosystem alignment.

Together, we are creating a new model for scientific discovery — one where breakthroughs are owned and advanced by the communities that believe in them.

Location: Germany (lab site TBC - right candidate informs final location)

Type: Senior IC role - no team to manage on day one; you hire your team in year two once the proof exists

The Role

Capsules. Tablets. Sterile compounding. We're building precisely‑dosed formulations of cognitive, performance, and longevity compounds - modafinil, bromantane, GLP‑1 analogs, BPC‑157, thymosin α‑1, and a growing pipeline of small‑molecule and peptide actives.

You will set our formulation standards, run the bench work, and be the person who can defend every excipient choice, every dissolution curve, and every sterility result. From active properties to qualified drug product - oral, injectable, topical - with documentation that holds up.

What You'll Do

• Design oral solid‑dose formulations (capsules and tablets) from active properties up - excipient selection, diluents, binders, disintegrants, flow agents, and lubricants matched to each compound's solubility, stability, and dosing profile
• Design sterile injectable formulations for our peptide pipeline - lyophile design, bulking agents, cryoprotectants, vial fill/finish at small scale, reconstitution protocols, and container‑closure compatibility. Hands‑on with EU GMP Annex 1 (sterile manufacturing) and applicable AMG/AMWHV requirements
• Own encapsulation, blending, and aseptic processing end to end: powder characterization, blend uniformity, content uniformity, capsule fill weight control, scale‑up from bench to production batches, and sterility assurance for the injectable side
• Solve hard actives. Bromantane and modafinil bring oral‑side challenges - low aqueous solubility, poor flow, dose accuracy at small fill weights. Peptides like BPC‑157, GLP‑1 analogs, and GHK‑Cu bring injectable‑side challenges - stability across the lyophile/reconstitution cycle, copper‑complex integrity, peptide aggregation. You develop the techniques that make all of them reproducible
• Build and run the analytical backbone: dissolution testing, assay/potency, content and weight uniformity, sterility (Ph. Eur. 2.6.1), endotoxin (Ph. Eur. 2.6.14), and stability programs (ICH Q1A - accelerated and long‑term) to establish shelf life
• Write documentation that holds up: master formulation records, batch records, specifications, and SOPs. Define what "in spec" means and enforce it. Clean data trails or it didn't happen
• Partner with sourcing and QC on raw‑material specs, incoming API characterization (identity, purity by HPLC, particle size), and supplier qualification. Build a qualified supplier network. Continuously improve - reduce variability, improve stability, lower cost‑per‑dose without compromising quality

Who You Are

• Defends decisions with data. You'd rather run the test than guess. When asked why you chose X over Y, you have a data‑grounded answer
• High bar on accuracy and sterility. It's people's health. Dose accuracy, reproducibility, and sterility are non‑negotiable - especially on injectables
• Expert in the room alone. You work well as the sole expert on day one. No team around you for the first year, and that doesn't slow you down
• Engineers around complexity. You see the regulatory complexity of the compound classes we work with clearly, and you engineer around it rather than pretending it isn't there

Required

• Approbation als Apotheker/in (German pharmacist license), or an EU‑recognized pharmacy qualification with a clear path to German licensure. Alternatively: a degree in pharmaceutics, pharmaceutical sciences, or industrial pharmacy (MSc/PhD) with equivalent hands‑on formulation depth
• 5+ years of hands‑on formulation experience in pharma, nutraceutical, compounding, or contract manufacturing - covering oral solid dose and at least one of: sterile injectables, topicals
• Deep working knowledge of excipient functionality and compatibility, and of encapsulation/tableting unit operations
• Practical command of dissolution, content uniformity, and stability study design and interpretation
• Experience formulating poorly‑soluble or low‑dose actives
• Working command of EU GMP (EudraLex Vol. 4), Annex 1 (sterile manufacturing), and the Apothekenbetriebsordnung (ApBetrO) or equivalent manufacturing‑pharmacy framework
• Rigor with documentation: batch records, specs, SOPs, and a clean data trail

Strongly Preferred

• Sterile injectable / lyophilization experience - peptide formulations specifically
• Background in a German Herstellungsapotheke, hospital pharmacy compounding unit, or EU‑licensed contract manufacturer
• Experience formulating GLP‑1 analogs (semaglutide, tirzepatide) or other peptide manufacturing under a quality‑grade framework
• Familiarity with cognitive/performance compounds, or with the broader peptide / longevity therapeutic landscape
• Hands‑on with HPLC, dissolution apparatus, particle sizing, Karl Fischer titration
• Comfort owning scale‑up from R&D batches to production
• Working proficiency in German (regulatory and documentation context) and English (team working language)

What We Offer

• A senior IC seat building the formulation function from scratch at a company at the intersection of biotech, blockchain, and AI
• Pre‑approved capex - you spec the equipment: lyophilizer, capsule filler, balance suite, HPLC, dissolution apparatus, Class II BSC
• The team you need, once you've proven the foundation

We are an equal opportunity employer. We are committed to equality and weaving a community that values diverse perspectives and experiences and are actively seeking a diverse pool of applicants. All employment decisions are made without regard to race, colour, national origin, ancestry, sex, gender, gender identity or expression, sexual orientation, age, genetic information, religion, disability, medical condition, pregnancy, marital status, family status, veteran status, or any other characteristic protected by law.