Pharmaceutical Scientist (R2-R4)

100 Eli Lilly and Company; Boston (MA); On-site; USD 101,000 - 123,000; Full time

Job summary

Eli Lilly and Company in Boston, MA is seeking a Pharmaceutical Scientist (R2‑R4) to develop nucleic acid–based formulations for therapeutic candidates, designing and optimizing lipid nanoparticle (LNP) formulations from small to mid‑scale and supporting in vivo studies.

Requirements include a Master’s degree in Chemistry or Pharmaceutical Science and at least 1 year in nucleic acid formulation or polymeric nanoparticle work, plus experience with nanoparticle characterization techniques.

Qualifications

• Master’s degree in Chemistry, Pharmaceutical Science, or related field.
• 1 year in nucleic acid formulation or polymeric nanoparticle formulation.
• 1 year in nanoparticle characterization techniques (DLS, zeta, Ribogreen).
• 1 year in preparing nanoparticle formulations for in vitro/in vivo studies.
• 1 year in wet lab biology techniques.
• Up to 10% travel (domestic/international).

Responsibilities

• Design, implement, and troubleshoot experiments for LNP formulations from small to mid‑scale.
• Characterize LNPs daily; assess stability via particle sizing, Ribogreen, osmometry.
• Optimize formulation methods for nucleic acid delivery.
• Support midscale production for large animal studies.
• Develop SOPs and test method documentation.
• Interpret data and maintain comprehensive study records.

Skills

Wet lab biology techniques

Formulation method design

Data interpretation & record keeping

Nanoparticle formulation experience

Analytical techniques for particles

Education

Master’s degree in Chemistry or Pharmaceutical Science

Tools

Dynamic Light Scattering

Zeta potential

Ribogreen assay

Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life‑changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, self‑less work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Eli Lilly and Company seeks a Pharmaceutical Scientist (R2‑R4) to develop nucleic acid‑based formulations for therapeutic candidates.

Responsibilities

• Design, implement, and troubleshoot laboratory experiments for lipid nanoparticle (LNP) formulations from small scale to mid‑scale.
• Perform daily characterization of LNPs, assessing stability using particle sizing, Ribogreen assay, and osmometry.
• Optimize current formulation methods and processes for delivery of nucleic acids.
• Screen optimal process to enable midscale production which supports large animal studies.
• Develop comprehensive standard operating procedures (SOPs) and generate test method documentation.
• Interpret and analyze data and maintain comprehensive records of multiple laboratory projects.
• Support downstream processing of nucleic acid‑based formulations.

Requirements

• Master’s degree in Chemistry, Pharmaceutical Science, or a related scientific field.
• 1 year of experience with researching nucleic acid formulation and characterization or 1 year of experience with polymeric nanoparticles formulation and characterization.
• 1 year of experience with analytical techniques for characterizing nanoparticles, including Dynamic Light scattering, Zeta potential, and Ribogreen.
• 1 year of experience with preparation of nanoparticle‑based formulations at scales sufficient to support in vitro and in vivo studies.
• 1 year of experience with wet lab biology techniques.
• 1 year of experience with designing formulation methods, composition, and process parameters.
• Up to 10% domestic and international travel required.
• Job location: Boston, MA.

Salary & Benefits

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $101,026.00 - $122,845.00 per year Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).

• eligibility to participate in a company-sponsored 401(k);
• pension;
• vacation benefits;
• eligibility for medical, dental, vision and prescription drug benefits;
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts);
• life insurance and death benefits;
• certain time off and leave of absence benefits;
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

EEO & Inclusion

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Company Culture

#WeAreLilly At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people. We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!