Pharmaceutical Scientist (R2-R4)

Initial Therapeutics, Inc.; Boston (MA); On-site; USD 101,026 - 122,845; Full time

Benefits offered by this job

Company-sponsored 401(k)

Comprehensive healthcare benefits

Vacation benefits

Job summary

Initial Therapeutics, Inc. is seeking a research scientist to design and implement laboratory experiments for lipid nanoparticle formulations in Boston, MA. The ideal candidate will have a Master's degree in Chemistry or Pharmaceutical Science and experience in nucleic acid formulation.

This full-time position offers a salary ranging from $101,026.00 to $122,845.00 per year along with a comprehensive benefits program, including eligibility for a company bonus and 401(k) participation.

Qualifications

• Master's degree in a relevant scientific field required.
• At least 1 year of experience with nucleic acid formulation and characterization.
• Experience with analytical techniques for characterizing nanoparticles needed.

Responsibilities

• Design and implement laboratory experiments for lipid nanoparticle formulations.
• Perform daily characterization of LNPs and assess stability.
• Optimize formulation methods for nucleic acid delivery.

Skills

Researching nucleic acid formulation

Characterizing nanoparticles

Wet-lab biology techniques

Designing formulation methods

Education

Master’s degree in Chemistry or Pharmaceutical Science

Tools

Dynamic Light Scattering

Zeta potential

Ribogreen assay

Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life‑changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Responsibilities

• Design, implement, and troubleshoot laboratory experiments for lipid nanoparticle (LNP) formulations from small scale to mid‑scale.
• Perform daily characterization of LNPs, assessing stability using particle sizing, Ribogreen assay, and osmometry.
• Optimize current formulation methods and processes for delivery of nucleic acids.
• Screen optimal process to enable mid‑scale production that supports large animal studies.
• Develop comprehensive standard operating procedures (SOPs) and generate test‑method documentation.
• Interpret and analyze data and maintain comprehensive records of multiple laboratory projects.
• Support downstream processing of nucleic acid‑based formulations.
• Travel up to 10% domestically and internationally as required.

Qualifications

• Master’s degree in Chemistry, Pharmaceutical Science, or a related scientific field.
• At least 1 year of experience with researching nucleic acid formulation and characterization or polymeric nanoparticles formulation and characterization.
• Minimum 1 year of experience with analytical techniques for characterizing nanoparticles, including Dynamic Light Scattering, Zeta potential, and Ribogreen.
• Minimum 1 year of experience preparing nanoparticle‑based formulations at scales sufficient to support in vitro and in vivo studies.
• Minimum 1 year of experience with wet‑lab biology techniques.
• Minimum 1 year of experience designing formulation methods, composition, and process parameters.

Location

Boston, MA

Compensation & Benefits

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $101,026.00 – $122,845.00 per year.

Full‑time employees will also be eligible for a company bonus (depending, in part, on company and individual performance). Lilly offers a comprehensive benefit program, including eligibility to participate in a company‑sponsored 401(k), pension, vacation benefits, medical, dental, vision and prescription drug benefits, flexible benefits (e.g., healthcare and/or dependent day‑care flexible spending accounts), life insurance, death benefits, certain time off and leave of absence benefits, and well‑being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities). Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

Equal Employment Opportunity

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.