Pathology Sr. Director

Initial Therapeutics, Inc.; United States; On-site; USD 150,000 - 200,000; Full time

Benefits offered by this job

Comprehensive employee benefits package

Discretionary annual bonus program

Stock-based long-term incentives

Job summary

Initial Therapeutics, Inc. is seeking a Pathology Senior Director to lead digital pathology efforts. The role involves ensuring dataset quality and executing AI-driven pathology workflows.

Qualifications include a DVM or equivalent with substantial experience in pathology and toxicology. This position offers competitive compensation and comprehensive benefits, including flexible work models and a generous employee benefits package.

Qualifications

• DVM or equivalent with extensive experience in pathology or toxicology.
• Experience with large-scale imaging datasets.
• PhD in pathology or toxicology preferred.

Responsibilities

• Ensure incoming datasets are delivered according to defined formats.
• Execute computational pathology workflows across AI model development.
• Provide pathology expertise for GLP and non-GLP studies.

Skills

Technical expertise

Strong stakeholder collaboration skills

Problem-solving skills

Education

DVM and 7 years of pathology or toxicology experience

Masters degree and 10 years of pathology or toxicology experience

Bachelors degree and 12 years of pathology or toxicology experience

Tools

Digital pathology pipelines

Annotation platforms

IHC assay workflows

Job description

Pathology Senior Director

What you will do

We are seeking a Pathology Senior Director within the Discovery and Toxicologic Pathology of the Translational Safety Regulatory Science function. The role focuses on digital pathology to accelerate the execution of computational pathology workflows, including AI/ML model development in discovery programs.

Key Responsibilities

• Ensure incoming datasets are delivered according to defined data formats, metadata standards, and project requirements.
• Translate scientific and model development requirements into structured dataset preparation tasks with pathology scientists and pathologists.
• Ensure imaging data, annotations, and metadata are suitable for downstream AI/ML model development, validation, and scientific analysis.
• Execute computational pathology workflows across AI model development and discovery projects to generate quantitative readouts supporting discovery and program decision-making within cloud-based data platforms (e.g., Deciphex Patholytics, Procia-Concentriq).
• Identify opportunities to improve data workflows, tooling, and operational processes within computational pathology.
• Stay informed about emerging data management practices, digital pathology technologies, and AI data standards.
• Provide pathology expertise to design and conduct GLP and non-GLP nonclinical safety studies, support progression of discovery and development programs, contribute pathology peer reviews, review integrated toxicology reports, serve as a contributing author to regulatory documents (INDs, NDAs/BLAs, IBs), and respond to Health Authority questions.

What we expect of you

We are looking for a leader who brings technical expertise, strategic thinking, and strong stakeholder collaboration skills.

Basic Qualifications

• DVM and 7 years of pathology or toxicology experience.
• OR
• Masters degree and 10 years of pathology or toxicology experience.
• OR
• Bachelors degree and 12 years of pathology or toxicology experience.

Preferred Qualifications

• DVM, Board Certification in Veterinary Anatomic Pathology (DACVP or comparable credential) and PhD in pathology or toxicology.
• At least 15 years of experience in the pharmaceutical sector as a discovery and toxicologic pathologist and an additional 5 years integrating pathology data into bioinformatics efforts in a pharmaceutical environment.
• Experience in pathology data management within pharmaceutical environments is highly desirable.
• Demonstrated experience working with large-scale imaging datasets (e.g., whole-slide images) and associated metadata in distributed or cloud environments and analysis outputs.
• Experience with annotation platforms, digital pathology pipelines, or whole-slide image analysis environments.
• Familiarity with IHC assay workflows and digital slide scanning.
• Experience interpreting target discovery pathology and toxicology studies.
• Strong problem‑solving skills and a solution‑oriented mindset, particularly when diagnosing and resolving data quality or workflow issues.

What you can expect of us

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities. Benefits include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
• Stock-based long‑term incentives.
• Award‑winning time‑off plans.
• Flexible work models where possible.

In any materials you submit, you may redact or remove age‑identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.