Operator II, Drug Substance

BioSpace; Bloomington (IN); On-site; USD 32,000 - 39,000; Full time

Benefits offered by this job

Leading pay and annual bonus

14 paid holidays

Health Insurance from day 1

Guaranteed 8% 401K contribution + 1:1

Parental & family leave

Tuition Assistance

Life & Disability Insurance

Employee Referral Awards

Job summary

Novo Nordisk in Bloomington, Indiana, is seeking a Manufacturing Operator for upstream biomanufacturing. This mid-level role involves high-independence execution of drug substance production, following GMP, safety, and quality standards.

Night shifts run 6:00 PM to 6:30 AM on a rotating schedule. The position supports manufacturing of biopharmaceutical products using cell culture, analytical equipment, and clean-room processes.

Qualifications

• Bachelor's Degree in related field of study required with zero years of experience
• Associate's Degree in related field with zero years of experience may be accepted
• High School Diploma or equivalent with one year of relevant experience may be accepted

Responsibilities

• Manipulation of cell culture in shake flasks and use of single-use bioreactors
• Operate cell culture equipment and basic biomanufacturing tools in a clean room
• Perform routine maintenance and calibration of analytical instruments as needed

Skills

Biomanufacturing

Cell culture

GMP

Process monitoring

Education

Bachelor's Degree

Associate's Degree

High School Diploma

Tools

ViCell

NOVA Bioprofile

Biosafety Cabinet

SUBs

CIP/SIP

Job description

About The Department

At Novo Nordisk, we want to make a difference. For more than 100 years, we have led the way in diabetes care. Being part of Novo Nordisk allows our employees to embark on the opportunity to help improve the quality of life for millions of people around the world.

About The Department

At Novo Nordisk, we want to make a difference. For more than 100 years, we have led the way in diabetes care. Being part of Novo Nordisk allows our employees to embark on the opportunity to help improve the quality of life for millions of people around the world.

Our Bloomington, Indiana site is a state‑of‑the‑art facility where we have an integrated model from process and formulation to clinical and commercial biomanufacturing and drug product fill/finish and packaging. The Bloomington campus is a recognized facility where talented teams work with innovators to help develop, manufacture and supply products to patients around the world.

What We Offer You

• Leading pay and annual performance bonus for all positions
• All employees enjoy generous paid time off including 14 paid holidays
• Health Insurance, Dental Insurance, Vision Insurance - effective day one
• Guaranteed 8% 401K contribution plus individual company match option
• Family Focused Benefits including 14 weeks paid parental & 6 weeks paid family medical leave
• Free access to Novo Nordisk-marketed pharmaceutical products
• Tuition Assistance
• Life & Disability Insurance
• Employee Referral Awards

At Novo Nordisk, you will find opportunities, resources, and mentorship to help grow and build your career. Are you ready to realize your potential? Join Team Novo Nordisk and help us make what matters.

The Position

Executes drug substance manufacturing operations with a high degree of independence, performing process steps, monitoring equipment, and troubleshooting routine issues in compliance with GMP, safety and quality requirements, to ensure reliable and consistent production of high-quality product. NOTE: This role works Nights; 6PM - 6:30AM (Rotating 3,2,2)

Relationships

Reports to Manager or above.

Essential Functions

This position is a mid-level position in the Upstream Manufacturing team and is the starting point to acquiring skills and training required for a cGMP biomanufacturing environment. The Manufacturing Operator is responsible for the manufacturing of biopharmaceutical products via production of genetically modified mammalian cells. This is achieved using a variety of equipment and processes including general analytical equipment, liquid handling equipment, cellular diagnostic machinery (ViCell, NOVA Bioprofile), Biosafety Cabinet, aseptic technique, various types of pumps, tube fusers, and tube sealers

Performs small- and large-scale cell culture work in a clean room environment under direct supervision, including, but not limited to:

• Manipulation of cell culture in shake flasks
• Single-use bioreactors (SUBs)
• Cell culture analysis using automated cell counters, bioanalyzers, sample preparation, osmometers, and any other applicable laboratory instrumentation
• Use of basic biomanufacturing equipment such as tube fusers, tube sealers, pumps, scales and balances
• Clean and Sterilize applicable processing equipment (CIP/SIP)
• Safely operates equipment within area
• Other duties as assigned

Physical Requirements

Frequent sitting, standing, walking, reading of written documents and use of computer monitor screen, reaching with hands and arms, talking, writing, listening. Occasional stooping, kneeling, crouching, bending, carrying, grasping. Frequent lifting and/or moving up to 20 pounds and occasional lifting and/or moving up to 50 pounds. Must comply with EHS responsibilities for the position. Working conditions will be Heating Ventilation and Air Conditioned controlled. Ability to operate within a clean room environment as needed.

Qualifications

Bachelor's Degree in related field of study from an accredited university required and a minimum of zero (0) year of relevant experience required

In lieu of Bachelor's Degree with zero (0) year of experience, may consider an Associate's Degree in related field of study from an accredited college or university with a minimum of zero (0) year of relevant experience required

In lieu of Bachelor's Degree with zero (0) year of experience, may consider a High School Diploma or equivalent with a minimum of one (1) year of relevant experience required

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk, we’re not chasing quick fixes - we're creating lasting change for long-term health. For over 100 years, we've been driven by a single purpose: to defeat serious chronic diseases and help millions of people live healthier lives. This dedication fuels our constant curiosity and inspires us to push the boundaries of what's possible in healthcare. We embrace diverse perspectives, seek out bold ideas, and build partnerships rooted in shared purpose. Together, we're making healthcare more accessible, treating and defeating diseases, and pioneering solutions that create change spanning generations. When you join us, you become part of something bigger – a legacy of impact that reaches far beyond today.

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.