Oncology Clinical Science Director

Verastem Oncology; Needham (MA); On-site; USD 200,000 - 260,000; Full time

Benefits offered by this job

Annual bonus

Equity compensation

Competitive benefits

Job summary

Verastem Oncology is seeking a Director, Clinical Scientist to provide leadership for assigned oncology studies and programs, shaping development strategy and regulatory submissions.

You will direct study design and execution, ensure data integrity across safety, efficacy, PK and biomarkers, author protocols, synopses, ICFs and CSR sections, and collaborate with investigators and partners. This role requires strong communication and travel up to 20%.

Qualifications

• Master's degree in life sciences with 12+ years of relevant work experience.
• Progressive biotech/pharma clinical development experience with leadership in oncology strategy, study execution, and data and safety analysis.
• Strong knowledge of GCP/GxP, the global drug development process, and current regulatory expectations (FDA/EMA).
• Ability to lead cross‑functional matrix teams, work independently, and exercise sound clinical judgment in a fast‑paced environment.
• Excellent analytical, interpersonal, verbal communication, influencing, and presentation skills.
• Ability to travel up to 20%.

Responsibilities

• Leads the clinical/scientific design and execution of assigned oncology trials with cross‑functional teams.
• Ensures clinical data integrity through hands‑on review and interpretation of safety, efficacy, PK, and biomarker data; translates findings into program insights.
• Oversees clinical science support from CROs and refines data review processes and workflows.
• Authors and leads key study and regulatory documents, including protocols, synopses, ICFs, investigator brochures, safety updates, CSR, and regulatory sections.
• Contributes to integrated development plans and study strategy, including risk assessment and decision points.
• Partners with investigators and stakeholders to ensure scientific oversight and regulatory compliance.
• Leads or supports investigator meetings and scientific forums; delivers clear presentations for internal and external audiences.
• Supports scientific communication through literature review and abstracts/presentations; stays current with oncology and regulatory environments.

Skills

Clinical leadership

Cross-functional collaboration

Data analysis

Regulatory knowledge

Presentation skills

Travel readiness

Education

Master's degree in life sciences

Job description

Verastem Oncology is seeking a Director, Clinical Scientist to provide leadership for assigned oncology studies and programs, shaping development strategy and regulatory submissions.

You will direct study design and execution, ensure data integrity across safety, efficacy, PK and biomarkers, author protocols, synopses, ICFs and CSR sections, and collaborate with investigators and partners. This role requires strong communication and travel up to 20%.