On-Site Clinical Research Associate — Travel-Heavy (West)

ICON; Denver (CO); On-site; USD 91,000 - 114,000; Full time

Benefits offered by this job

Health insurance

Retirement planning

Global EAP LifeWorks

Flexible country-specific benefits

Job summary

ICON is seeking a Clinical Research Associate for Denver in a sponsor-dedicated model, contributing to trials across multiple therapeutic areas.

You will perform site visits, ensure ICH-GCP compliance, manage CTMS/eTMF documentation, and support site staff training.

Candidates should have a Life Sciences degree or be an RN, 2+ years' on-site monitoring, and be able to travel up to 60-75% for regional sites.

Qualifications

• 2+ years of on-site monitoring experience in pharma or CRO.
• Experience monitoring across multiple therapeutic areas.
• Proficient in ICH-GCP and regulatory requirements; CTMS/eTMF experience.

Responsibilities

• Serve as the primary contact between investigational sites and the sponsor.
• Conduct site visits including selection, initiation, routine monitoring, and close-out.
• Ensure site compliance with ICH-GCP, SOPs, and regulations.
• Maintain up-to-date documentation in CTMS and eTMF systems.
• Support and track site staff training and maintain compliance records.
• Monitor patient safety, ensuring timely AE/SAE/PQC reporting.
• Support subject recruitment and retention efforts at the site level.
• Oversee drug accountability and proper storage, return, or destruction.
• Resolve data queries and drive timely, high-quality data entry.
• Document site progress and escalated risks or issues to the clinical team.
• Assist in tracking site budgets and ensuring timely site payments.

Skills

On-site monitoring

Travel flexibility

Clear communicator

Education

Bachelor's degree Life Sciences

RN (Registered Nurse)

Tools

CTMS

eTMF

Job description

ICON is seeking a Clinical Research Associate for Denver in a sponsor-dedicated model, contributing to trials across multiple therapeutic areas.

You will perform site visits, ensure ICH-GCP compliance, manage CTMS/eTMF documentation, and support site staff training.

Candidates should have a Life Sciences degree or be an RN, 2+ years' on-site monitoring, and be able to travel up to 60-75% for regional sites.