Night-Shift Downstream Purification Tech III (Rotating 2-2-3)

Actalent; Morrisville (NC); On-site; USD 51,000 - 58,000; Full time

Benefits offered by this job

Health benefits

401(k) plan

Life Insurance

Disability coverage

HSA

Transit benefits

Employee assistance program

Paid time off

Job summary

Actalent seeks a Night Shift Production Technician III to perform downstream recovery and purification in a regulated biomanufacturing environment. You will document manufacturing steps, monitor processes, and execute control strategies on a rotating 2-2-3 day/night schedule.

The role supports a 24/7 operation, requiring flexibility, strong attention to detail, and collaboration with cross-functional teams to ensure quality, safety, and regulatory compliance.

Qualifications

• Candidates must have a cGMP manufacturing background and be able to document activities clearly.
• Experience executing downstream recovery or purification processing in a regulated environment.
• Proficiency with process monitoring and in-process testing (pH, conductivity, visual inspection).
• Familiarity with automated control and MES/CMMS documentation.

Responsibilities

• Execute and document downstream recovery and purification steps in a cGMP environment.
• Prepare buffers and solutions and perform glass-wash tasks as needed.
• Monitor processes and perform in-process testing to ensure reliable operation.
• Document activities and manage electronic batch records.
• Initiate deviations and work orders as required to maintain control.
• Collaborate with cross-functional teams and provide guidance as needed.

Skills

cGMP manufacturing

Process monitoring

Documentation

Team collaboration

Safety knowledge

2-2-3 rotating shift

BioProcess understanding

Education

High school diploma or GED

Associate degree in life science/engineering

Bachelor's degree in life science/engineering

Equivalent military training

Tools

DeltaV

800xA

Unicorn

MES

CMMS

Job description

Actalent seeks a Night Shift Production Technician III to perform downstream recovery and purification in a regulated biomanufacturing environment. You will document manufacturing steps, monitor processes, and execute control strategies on a rotating 2-2-3 day/night schedule.

The role supports a 24/7 operation, requiring flexibility, strong attention to detail, and collaboration with cross-functional teams to ensure quality, safety, and regulatory compliance.