Neuroscience Associate Professor - Optogenetics & Imaging

Baylor College of Medicine; Town of Texas (WI); On-site; USD 120,000 - 180,000; Full time

Job summary

Baylor College of Medicine in Houston, TX, invites applications for an Associate Professor focused on neuroscience in the St-Pierre lab. The role centers on characterizing light-responsive proteins, including GEVIs and optogenetic silencers, to advance imaging and control of neural activity.

Responsibilities include patch clamp work in HEK293 cells and neurons, GEVI evaluation in culture and brain slices, site-directed mutagenesis, data analysis, and mentoring junior researchers.

Qualifications

• Experience with patch clamp electrophysiology in mammalian cells or neurons.
• Experience using fluorescence and two-photon microscopy to study light-responsive proteins.
• Familiarity with GEVI performance in cell culture and brain slice preparations.
• Proficiency in site-directed mutagenesis to optimize protein properties.
• Ability to discover and clone novel channelrhodopsins and fluorescent biosensors.

Responsibilities

• Characterize light-gated ion channels (KCRs, ACRs) using patch clamp electrophysiology.
• Evaluate GEVI performance in mammalian cell culture and brain slices using fluorescence and two-photon imaging.
• Perform structure-function analyses to optimize protein properties.
• Maintain and troubleshoot electrophysiology rigs and imaging systems.
• Present findings at lab meetings and conferences; contribute to grants and manuscripts.

Skills

Patch clamp

Two-photon microscopy

GEVI

KCRs

ACRs

Mutagenesis

Mammalian culture

Brain slices

Data analysis

Grant writing

Tools

HEK293

Job description

Baylor College of Medicine in Houston, TX, invites applications for an Associate Professor focused on neuroscience in the St-Pierre lab. The role centers on characterizing light-responsive proteins, including GEVIs and optogenetic silencers, to advance imaging and control of neural activity.

Responsibilities include patch clamp work in HEK293 cells and neurons, GEVI evaluation in culture and brain slices, site-directed mutagenesis, data analysis, and mentoring junior researchers.