Neural Imaging Engineer – Cellular Physiology Optogenetics

MassBio; Cambridge (MA); On-site; USD 75,000 - 110,000; Full time

Benefits offered by this job

Health, dental, vision

Retirement matching

Family benefits

Job summary

Mindspan Institute in Cambridge, MA is building novel tools to analyze the human brain, with a mission to advance health by openly sharing discoveries.

The role is an in-person engineering-oriented science position focused on recording, controlling, analyzing, and visualizing neural activity at cellular and subcellular levels. You will optimize recording quality, document protocols, and collaborate across disciplines to push boundaries.

Qualifications

• B.S./B.A. in bioengineering, neuroscience, biophysics, chemistry, or related field.
• Hands-on neural tissue handling, cell culture, histology, and fluorescence microscopy.
• Ability to build, modify, troubleshoot, and improve complex experimental systems.
• Excellent experimental judgment and scientific rigor.

Responsibilities

• Execute and optimize cellular activity imaging experiments.
• Produce high-quality voltage imaging and synaptic recording data from iPSC-derived neurons and brain slices.
• Characterize optogenetics and voltage sensor performance.
• Evaluate gene expression systems.
• Documentation and training: keep protocol records that others can execute, with the reasoning behind each parameter.

Skills

Data analysis

Experimental judgment

Scientific rigor

Education

B.S./B.A. in related field

Tools

Python

C++

MATLAB

ImageJ

Job description

Mindspan Institute in Cambridge, MA is building novel tools to analyze the human brain, with a mission to advance health by openly sharing discoveries.

The role is an in-person engineering-oriented science position focused on recording, controlling, analyzing, and visualizing neural activity at cellular and subcellular levels. You will optimize recording quality, document protocols, and collaborate across disciplines to push boundaries.