MSAT Director, Cell Therapy Process Transfer

Sana Biotechnology, Inc.; Cambridge, Northern (MA, KY); Hybrid; USD 200,000 - 250,000; Full time

Benefits offered by this job

401(k) Plan with employer match

Tuition Reimbursement

Employee Stock Purchase Plan

Commuter subsidy

Generous health coverage

Job summary

Sana Biotechnology, Inc. is hiring an MSAT Director to lead an MSAT team focused on Phase I manufacturing of PSC-derived pancreatic islet cells for type 1 diabetes. You will manage technology transfer to an external partner, oversee training, and drive documentation and investigations.

You will collaborate with Quality, External Manufacturing, and Supply Chain to ensure batch disposition and regulatory readiness, while mentoring a high-performing, cross-disciplinary team in a fast-paced setting.

Qualifications

• BSc in Chemical, Biological, or Biomedical Engineering with 10+ years or equivalent experience.
• >5 years of experience supporting early phase cell therapy manufacturing including technology transfers.
• Experience with cGMP requirements and working in a regulated environment (person-in-plant and GMP operator).
• Knowledge of PSC culture and differentiation biology toward pancreatic islets.
• Experience managing a team of 3+ direct reports.
• Detail-oriented with strong problem-solving, technical writing, and verbal communication skills.
• Ability to work in multidisciplinary teams, meet deadlines, and prioritize multiple projects.
• Aptitude for working in a fast-paced matrix environment.

Responsibilities

• Lead a team of 2–4 individuals supporting Phase I manufacturing of a PSC-derived pancreatic islet cell therapy product.
• Partner with CDMO technical teams to achieve manufacturing readiness and address technical challenges.
• Oversee people-in-plant activities, operator training, documentation, and process execution.
• Author CMC sections for regulatory filings (IND module 3) and other technical documents.
• Collaborate with Quality to close deviations, analyze manufacturing trends, and recommend process improvements.
• Lead investigations and troubleshoot process execution challenges including root cause analysis.
• Perform comparability studies with Research and PD teams to assess tech transfer success.
• Engage in constructive feedback to support growth and development of team members.
• Demonstrate ability to influence across multidisciplinary teams while prioritizing multiple projects.

Skills

Leadership

cGMP knowledge

Cell therapy knowledge

Problem solving

Documentation & writing

Multidisciplinary teamwork

Education

BSc in Chemical/Biomedical Engineering

Tools

DoE

Flow cytometry

RCA

Job description

Sana Biotechnology, Inc. is hiring an MSAT Director to lead an MSAT team focused on Phase I manufacturing of PSC-derived pancreatic islet cells for type 1 diabetes. You will manage technology transfer to an external partner, oversee training, and drive documentation and investigations.

You will collaborate with Quality, External Manufacturing, and Supply Chain to ensure batch disposition and regulatory readiness, while mentoring a high-performing, cross-disciplinary team in a fast-paced setting.