Molecular Technologist - Solid Tumor (Multiple Shifts)

Caris Life Sciences; Phoenix, Northern (AZ, KY); Hybrid; USD 65,000 - 90,000; Full time

Job summary

Caris Life Sciences seeks a Molecular Technologist – Solid Tumor to perform high complexity molecular techniques including nucleic acid extraction and NGS. You will work under supervision, following SOPs, and contribute to quality systems and data documentation.

The role requires a degree in science with practical lab experience; familiarity with CAPA, LIMS, and routine QC activities is preferred and you will be part of a team delivering precise cancer care solutions.

Qualifications

• Bachelor’s degree in scientific field required; 0–3+ years of relevant molecular lab experience may be considered.
• Demonstrate skills in technical data interpretation and ability to troubleshoot.
• Proficient in Microsoft Office programs (Word, Excel, Outlook).

Responsibilities

• Follows SOPs and performs molecular techniques including nucleic acid extraction, PCR, and NGS.
• Operates and maintains liquid handling robots.
• Maintains laboratory equipment, accessories and instruments used in clinical processing.
• Prepares CAPA documents for nonconformance events observed during testing.
• Participates in continuous process improvements and proficiency testing.
• Uses LIMS to track and document day-to-day tasks.

Skills

Technical data interpretation

Troubleshooting

Education

Bachelor’s degree in scientific field

Bachelor’s degree in chemical, biological, clinical or medical laboratory science

Tools

Microsoft Office

Job description

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

The Molecular Technologist – Solid Tumor is responsible for performing routine high complexity molecular techniques that include but are not limited to nucleic acid extractions and next generation sequencing (NGS). This position works under the direction of the supervisor and follows standard laboratory procedures and policies. Molecular Technologists develop foundational skills in molecular workflows, quality systems and data documentation while contributing to team goals.

Job Responsibilities

Follows established laboratory protocols governed by standard operating procedures (SOPs). Performs molecular techniques with proficiency: nucleic acid extraction; quantification and normalization; PCR; DNA methylation analysis; and next generation sequencing (NGS). Operates and maintains liquid handling robots. Maintains laboratory equipment, accessories and instruments used in clinical processing by performing routine maintenance. Prepares Corrective and Preventive Action (CAPA) documents for nonconformance events observed during the pre-analytical, analytical, and post-analytical clinical laboratory testing. Participates in continuous process improvements, validations and proficiency testing. Proficiency in the Laboratory Information Management (LIMS) tracking system to accurately perform and record day-to-day tasks. Each individual performs only those high complexity tests that are authorized by the laboratory director and require a degree of skill commensurate with the individual’s education, training, technical abilities and experience. Follow the laboratory’s procedures for specimen handling and processing. Adhere to and document all the laboratory’s quality control policies and activities as governed by FDA, CAP, CLIA, NYS and ISO regulatory standards. Perform instrument maintenance and procedural calibrations. Follow the laboratory’s established policies and procedures whenever test systems are not within the laboratory’s established acceptable levels of performance. Be capable of identifying problems that may adversely affect test performance or reporting of test results and either must correct the problems or immediately notify the supervisor, manager or director. Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications; and Perform high complexity testing under the onsite, direct supervision of a general supervisor as defined in the CLIA regulations. Accepts other duties as assigned.

Required Qualifications

We are seeking to hire a Molecular Technologist with varying levels of experience. Molecular Technologist I - Bachelor’s degree in scientific field required and may have less than 1 year of relevant work experience. Molecular Technologist II – Bachelor’s degree in scientific field required and 3+ years of relevant molecular laboratory experience. Bachelor's degree in chemical, biological, clinical or medical laboratory science, or medical technology from an accredited institution. Demonstrate skills in technical data interpretation and ability to troubleshoot. Proficient in Microsoft Office programs, such as Word, Excel, and Outlook. General working knowledge of the internet for business use, and skilled in operating office equipment.

Preferred Qualifications

Master's degree in a chemical, biological, clinical or medical laboratory science, or medical technology from an accredited institution. Nucleic acid extraction experience. Next Generation Sequencing Experience. Knowledge of laboratory safety procedures for biohazards and chemicals, as well as quality control procedures and regulations.

Physical Demands

Will work at a computer that requires the use of copiers and PDF scanners. Visual acuity and analytical skill to distinguish fine detail. Ability to pass a visual color discrimination test. Manual dexterity to use common laboratory equipment and perform sterile techniques as required. Must possess ability to sit and/or stand for long periods of time. Must possess ability to perform repetitive motion. Ability to lift up to 30 pounds. May be required to handle and/or may have exposure to blood-borne pathogens, extreme temperatures, high noise levels, fumes and bio-hazardous material/chemicals including formaldehyde, xylene, Clorox bleach, DAB and alcohol, which emit fumes. Formaldehyde, xylene, and DAB are carcinogenic.

Shift Openings

Other Shift Openings: 2nd Shift (1:30pm-12:00am) and 3rd Shift (9:30pm-8:00am). This position will require evenings/nights, weekends and Holidays.

Conditions of Employment

Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification. This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Equal Opportunity

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Caris Life Sciences is a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine through quality and innovation. Caris is committed to quality and excellence at our state-of-the‑art laboratories. Learn more about our tissue lab and the advanced technologies that are helping improve the lives of cancer patients.