Microbiologist III - 2nd Shift

BioSpace; Irvine (CA); On-site; USD 61,000 - 66,000; Full time

Benefits offered by this job

Medical, Dental, Vision

401K

Life Insurance

HSAs

Job summary

Siegfried Irvine, CA seeks a Senior Microbiologist on the 2nd Shift (2:00 PM - 10:30 PM) to support sterile pharmaceutical manufacturing. You will perform environmental monitoring, antimicrobial effectiveness testing, method validation, and investigations, while contributing to quality and patient safety.

This hands-on laboratory position offers leadership growth, opportunities to mentor others, and a focus on contamination control, product quality, and regulatory readiness within a growing CDMO.

Qualifications

• Bachelor's degree in Microbiology or related field; advanced degree preferred.
• 8-10+ years in pharmaceutical microbiology for sterile manufacturing.
• Experience with method validation and aseptic operations.
• Strong technical writing and documentation skills.

Responsibilities

• Perform environmental monitoring and microbiological testing of materials and products.
• Provide direct microbiology support for sterile manufacturing operations.
• Lead investigations for OOT, OOS, deviations, and contamination control.
• Author and review protocols, reports, and investigations.
• Mentor microbiologists and support regulatory inspections.

Skills

Microbiology expertise

cGMP knowledge

Technical writing

Method validation

Aseptic processing

Investigation leadership

Education

Bachelor's degree in Microbiology

Advanced degree preferred

Tools

LIMS

Electronic lab systems

Job description

"Expect to grow", personally and professionally: At Siegfried, we offer exciting challenges and ample opportunities to showcase your talents. As a trusted and respected partner to the pharmaceutical industry, we uphold the highest standards in safety, quality and sustainability, while fostering a culture that empowers you to thrive. Join a rapidly expanding global company, where diverse perspectives and experiences come together in a collaborative environment. Here, you'll find a workplace that values both collective success and your individual contributions—offering long‑term opportunities to grow and make an impact.

Your Role

Microbiologist III - 2nd Shift (2 PM - 10:30 PM)

If you've built your microbiology career supporting pharmaceutical manufacturing and are looking for an opportunity to continue growing your technical expertise while remaining hands‑on in the laboratory, this could be the next step you're looking for.

As a Microbiologist III on our 2nd Shift team, you will play an important role in supporting sterile manufacturing operations within a growing pharmaceutical CDMO while taking on the kind of work that helps experienced microbiologists continue to grow professionally. You will be actively involved in laboratory operations while expanding your role in microbiological investigations, technical writing, method verification activities, and the programs that help ensure product quality, contamination control, and patient safety.

We are looking for an experienced senior microbiologist who is naturally curious, enjoys solving complex scientific challenges, and takes pride in producing high‑quality work. Whether you're supporting antimicrobial effectiveness testing, investigating unexpected results, authoring technical reports, or helping drive sound scientific decisions, you'll have opportunities to apply your expertise in meaningful ways while building the skills and experience that prepare you for future lead-level responsibilities.

This role is a great fit for someone who enjoys both the science and the opportunity to share knowledge, mentor others, and serve as a trusted technical resource. Every day, your work helps support our clients, our manufacturing operations, and the patients who rely on the treatments we produce.

Your Profile

Why You'll Love This Role

• Continue growing your expertise in pharmaceutical microbiology while remaining hands‑on in the laboratory
• Gain valuable leadership experience while staying connected to the science
• Be the microbiologist colleagues turn to for technical expertise and scientific guidance
• Mentor developing microbiologists and help strengthen the team's technical capabilities
• Join a growing pharmaceutical CDMO where your work directly impacts product quality, client success, and patient safety

What You'll Do

• Perform microbiological testing of environmental monitoring samples, utilities, raw materials, in-process samples, and finished drug products.
• Provide direct microbiology support for sterile and aseptic manufacturing operations.
• Perform specialized testing, including Antimicrobial Effectiveness Testing (AET).
• Execute microbiological method validation and qualification studies, including protocol execution, data analysis, and report generation.
• Lead OOT, OOS, deviation, and contamination control investigations.
• Evaluate microbiological and environmental monitoring data to identify trends and support sound scientific decision‑making.
• Author and review technical protocols, reports, investigations, and other scientific documentation.
• Support new product introductions, process improvements, technology transfers, and regulatory inspections.
• Mentor fellow microbiologists and help strengthen technical capabilities across the team.

Who Thrives in This Role

You're naturally curious, enjoy solving complex scientific challenges, and take pride in producing high‑quality work. Colleagues value your expertise and look to you as a trusted resource when microbiological questions arise.

You enjoy both the science and the opportunity to share knowledge, support others, and contribute to manufacturing operations that help deliver treatments patients depend on.

What You'll BringRequired Qualifications

• Bachelor's degree in Microbiology or a closely related scientific discipline (advanced degree preferred).
• 8-10+ years of pharmaceutical microbiology experience supporting sterile manufacturing operations.
• Experience executing microbiological method validation and qualification studies.
• Experience providing direct microbiology support to aseptic manufacturing operations.
• Experience supporting Antimicrobial Effectiveness Testing (AET).
• Experience leading OOT, OOS, deviation, and microbiology investigations.
• Strong knowledge of aseptic processing, contamination control, environmental monitoring, and cGMP requirements.
• Strong technical writing skills with experience authoring protocols, reports, investigations, and scientific documentation.

Preferred Qualifications

• Experience working in a pharmaceutical CDMO environment.
• Experience supporting regulatory inspections and customer audits.
• Familiarity with USP microbiology requirements.
• Experience with LIMS and other electronic laboratory systems.
• Experience mentoring or providing technical guidance to other microbiologists.

2nd Shift: 2:00 PM - 10:30 PM, Monday through Friday

Target Pay Range: $44-$48/hour + 10% Shift Differential

Individual compensation packages are based on various factors unique to each candidate, including skill set, experience, qualifications, and other job-related reasons.

Your Benefits

• Medical, Dental, Vision
• Flexible Spending & HSA Options
• Life Insurance, Short & Long Term Disability
• Pet Insurance
• 401K

Founded in 1873 in Zofingen, Switzerland, Siegfried has grown into a global network of 16 sites across three continents. With a team of more than 4,200 highly skilled professionals, we take the innovations of our pharmaceutical customers to industrial scale and manufacture safe drugs for patients worldwide. As a fully integrated CDMO, Siegfried is one of the few organizations today that can carry out the development and manufacturing of APIs and finished dosage forms under one roof. This unique combination of know‑how and experience makes us the most trusted partner in the pharmaceutical industry.