Medicinal Chemist — Lead Discovery & Optimization

Initial Therapeutics, Inc.; Indianapolis (IN); On-site; USD 100,526 - 163,440; Full time

Benefits offered by this job

Company bonuses

401(k) plan

Medical and dental coverage

Fitness benefits

Job summary

Initial Therapeutics, Inc. is seeking a Medicinal Chemist to formulate hypotheses and design novel small molecules. The role requires collaboration with CROs and maintaining a strong safety culture while optimizing compounds for medicinal chemistry.

The ideal candidate has a Master’s degree with 4+ years of experience or a PhD and 1 year in drug discovery. Competitive salary range, along with comprehensive benefits including bonuses, a 401(k) plan, and medical coverage.

Qualifications

• 4 years of experience in synthetic organic or medicinal chemistry.
• Experience supporting drug discovery at the molecular design stage.
• Familiarity with targeted protein degradations, siRNA, ADCs, and oral peptides.

Responsibilities

• Formulate hypotheses and synthesize novel small molecules.
• Optimize lead compounds for potency and selectivity.
• Collaborate with external resources for chemistry needs.

Skills

Synthetic organic chemistry

Medicinal chemistry

Molecular design

Drug discovery

Education

Master’s degree in Chemistry or related field

PhD in Chemistry or related field

Job description

Initial Therapeutics, Inc. is seeking a Medicinal Chemist to formulate hypotheses and design novel small molecules. The role requires collaboration with CROs and maintaining a strong safety culture while optimizing compounds for medicinal chemistry.

The ideal candidate has a Master’s degree with 4+ years of experience or a PhD and 1 year in drug discovery. Competitive salary range, along with comprehensive benefits including bonuses, a 401(k) plan, and medical coverage.