Medical Science Liaison

personalisinc; United States; Remote; USD 120,000 - 160,000; Full time

Job summary

Personalis is seeking a Medical Science Liaison (MSL) in Oncology to serve as a field-based scientific expert for NeXT Personal® and our ctDNA assays. You will engage clinicians, researchers, and healthcare professionals to support the oncology portfolio and provide education to internal and external stakeholders.

The role focuses on scientific exchange, advisory-building with key opinion leaders, and active promotion of clinical value and appropriate test use.

Qualifications

• Advanced degree in a relevant field (e.g., oncology, genomics).
• Proven ability to present complex data clearly to diverse audiences.
• Experience engaging key opinion leaders and investigators.

Responsibilities

• Deliver clinical and scientific presentations on oncology data to clinicians and researchers.
• Build and maintain relationships with KOLs and leading physicians.
• Represent the company at conferences and educational events.
• Travel ~50% to support field activities.

Skills

Scientific communication

KOL engagement

Clinical education

Field travel

Education

Advanced degree (PhD/MD)

Job description

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Territory: West Coast

Summary

As a member of the Medical Affairs team, the Medical Science Liaison (MSL) - Oncology serves as a field-based scientific expert who engages clinicians, researchers, and other healthcare professionals to support Personalis' oncology genomics portfolio. This role has a primary focus on NeXT Personal® , an ultra-sensitive, tumor-informed circulating tumor DNA (ctDNA) assay designed for minimal residual disease (MRD) detection, while also providing broader scientific support across our product line. The MSL acts as a bridge between Personalis and the healthcare community, facilitating the exchange of medical information, building key relationships with opinion leaders, and driving awareness of our cutting-edge assays. In addition, the MSL provides field-based commercial support to the clinical sales team through education and training initiatives, ensuring that both internal teams and external stakeholders are well-informed about the clinical value and appropriate use of our products.

Days onsite

Remote

Core Responsibilities

• Clinical and Scientific Communication: Deliver clinical and scientific presentations on data supporting Personalis' oncology products - with special emphasis on the NeXT Personal MRD assay - to healthcare providers, academic groups, and other stakeholders. Tailor complex genomic and clinical information to suit diverse audiences, ensuring clear understanding of our test's utility.
• KOL Engagement: Establish and maintain strong collaborative relationships with key opinion leaders (KOLs) and leading physicians in the oncology community. Engage academic and community KOLs through regular scientific exchange to promote understanding and adoption of our novel ctDNA and genomic technologies. Identify opportunities to involve KOLs in advisory boards, speaker programs, or research collaborations that enhance the visibility of Personalis' assays.
• Clinical Advocacy & Education: Represent Personalis at scientific and clinical conferences, symposia, and other educational events. This includes supporting PIs with clinical study data or posters, participating in panel discussions, and hosting educational workshops or grand rounds to highlight the clinical evidence and best practices for using our ctDNA assay and broader test portfolio. Ensure consistent and medically accurate messaging in all external engagements.
• Field Travel: Travel frequently (approximately 50% of the time) to execute the above field responsibilities. This includes local and overnight travel for HCP meetings, conference attendance, internal training sessions, and other field engagements. (A valid driver's license and the ability to travel by air are required.) Flexibility to occasionally travel on short notice or attend weekend events is expected as part of this field-based role.

Additional Responsibilities

• Research Support: Support and coordinate clinical research and evidence-generation initiatives involving Personalis' tests. Identify and liaise with potential clinical trial sites and investigators for company-sponsored studies or investigator-initiated trials , particularly those evaluating MRD with NeXT Personal. Facilitate collaboration with researchers by providing scientific expertise, assisting in study site onboarding, and monitoring study progress in accordance with appropriate guidelines.
• Medical Content Development: Contribute medical and scientific expertise to the development and review of content such as slide decks, white papers, training modules, and publications to ensure accuracy and alignment with current data. Critically appraise new research findings and incorporate them into educational materials and talking points, working closely with Marketing and Medical Affairs on messaging that meets both scientific and compliance standards.
• Insight Generation: Continuously gather insights from the field and stay abreast of emerging research in oncology and molecular diagnostics. Monitor new studies, competitive developments, and clinical guidelines related to MRD, ctDNA, and precision oncology. Share relevant scientific updates and field feedback with internal teams (Medical Affairs, R&D, Marketing) to inform strategy, product development, and data needs.

Qualifications and Experience

Education: Advanced degree in a