Medical Director, Oncology

Avance Clinical Pty Ltd.; United States; On-site; USD 230,000 - 360,000; Full time

Benefits offered by this job

Salary package

Flexible work

Tech systems

Challenging projects

Career progression

Supportive leadership

Global CRO stability

Job summary

Avance Clinical is seeking a Medical Director in Oncology to provide medical and scientific leadership across oncology clinical development programs. The role involves serving as Medical Monitor, guiding protocol design, safety oversight, and cross-functional collaboration to ensure data quality and patient safety in all phases of oncology research.

You will engage with sponsors, investigators, and internal teams, contributing to business development through proposals and meetings, and mentoring

Qualifications

• Medical degree (MD or equivalent) required.
• Specialist training, board certification, fellowship, or equivalent qualification in Oncology preferred.
• Significant experience in oncology clinical research in CRO/pharma/academic settings.
• Experience as Medical Monitor or medical oversight for oncology trials.

Responsibilities

• Provide medical and scientific leadership for oncology programs as Medical Monitor and SME.
• Review eligibility, protocol compliance, safety events, and data integrity.
• Input on dose-escalation decisions and safety/oversight committees.
• Support investigators with protocol inquiries and clinical guidance.
• Deliver oncology expertise across study teams and departments.
• Contribute to protocol/informed consent and study documents.
• Advise on patient populations, endpoints, and safety monitoring.

Skills

Medical leadership

Oncology expertise

Data interpretation

Regulatory knowledge

Team mentoring

Sponsor interactions

Cross-functional collaboration

Communication skills

Education

MD or equivalent

Board/Fellowship in Oncology

Job description

Broad Purpose

Avance Clinical is a Contract Research Organisation which offers specialised services supporting drug development for the pharmaceutical and biotechnology industry.

Broad Purpose

Avance Clinical is a Contract Research Organisation which offers specialised services supporting drug development for the pharmaceutical and biotechnology industry.

The Medical Director, Oncology provides medical and scientific leadership across oncology clinical development programs and serves as a key subject matter expert within Avance Clinical's Oncology Centre of Excellence. The role is responsible for providing medical oversight, scientific guidance, protocol review and development support, safety expertise, and therapeutic leadership across all phases of oncology clinical research.

Working collaboratively with sponsors, investigators, Clinical Operations, Business Development, Biostatistics, Regulatory Affairs, Pharmacovigilance, and other cross-functional teams, the Medical Director supports the successful design, execution, and delivery of oncology clinical trials while ensuring scientific integrity, patient safety, data quality, and regulatory compliance.

The Medical Director also contributes oncology expertise to business development initiatives through sponsor engagements, proposal support, feasibility assessments, bid defense meetings, and strategic discussions, helping position Avance Clinical as a preferred partner for oncology drug development.

Core Responsibilities

• Provide medical and scientific leadership for oncology clinical development programs, serving as Medical Monitor and oncology subject matter expert across study design, execution, and delivery.
• Review subject eligibility, protocol compliance, safety events, and clinical data to support subject protection and data integrity.
• Provide medical input into dose-escalation decisions, Data Review Committees, Safety Review Committees, and other study oversight activities.
• Support investigators by responding to protocol and medical inquiries and providing clinical guidance throughout study conduct.
• Deliver oncology therapeutic area expertise across study teams and departments.
• Contribute to the design and review of clinical trial protocols, informed consent forms, study manuals, and other clinical documents.
• Advise on patient populations, inclusion/exclusion criteria, study endpoints, efficacy assessments, and safety monitoring requirements.
• Review and interpret emerging clinical, scientific, and safety data relevant to assigned studies and therapeutic areas.
• Partner with Regulatory Affairs, Medical Writing, Pharmacovigilance, and Clinical Operations teams to ensure high-quality study delivery.
• Participate in investigator meetings, sponsor meetings, safety discussions, and regulatory interactions as required.
• Provide oncology training, mentoring, and scientific guidance to internal teams.
• Contribute medical expertise to business development activities including proposals, RFIs, RFPs, bid-defense meetings, and sponsor discussions.
• Support scientific presentations, publications, conference participation, and Oncology Centre of Excellence initiatives.
• Other duties as directed by Line Management consistent with skills, experience, and qualifications.

Departmental Responsibilities

• Act as a key Oncology Centre of Excellence subject matter expert across all phases of clinical development.
• Provide strategic oncology guidance to internal stakeholders and project teams.
• Support capability development initiatives within oncology and related therapeutic areas.
• Participate in departmental process improvements, training activities, and quality initiatives.
• Contribute to the maintenance and expansion of oncology knowledge resources, investigator networks, and key industry relationships.
• Collaborate with cross-functional leaders to strengthen Avance Clinical's oncology service offerings.
• Represent Avance Clinical at scientific meetings, industry conferences, and sponsor engagements.
• Promote a culture of scientific excellence, quality, compliance, and patient safety.

Qualifications, Skills And Experience

• Medical degree (MD or equivalent) required.
• Specialist training, board certification, fellowship, or equivalent qualification in Oncology, Hematology-Oncology, or a related oncology discipline preferred.
• Significant experience in oncology clinical research, preferably within CRO, biotechnology, pharmaceutical, academic research, or healthcare environments.
• Demonstrated experience serving as a Medical Monitor or providing direct medical oversight for oncology clinical trials.
• Strong understanding of oncology drug development, clinical trial methodology, safety monitoring, and regulatory requirements.
• Experience supporting early-phase and/or mid-phase oncology studies, including dose-escalation and complex clinical development programs.
• Sound clinical judgment with the ability to assess patient safety, protocol compliance, and emerging clinical data.
• Ability to communicate complex medical and scientific concepts effectively to sponsors, investigators, and internal stakeholders.
• Experience collaborating effectively within multidisciplinary clinical research teams.
• Excellent written and verbal communication skills.
• Ability to mentor and provide scientific leadership within a matrix environment.
• Experience contributing to proposals, sponsor interactions, and business development activities preferred.
• Established professional relationships within the oncology community are advantageous.
• Willingness and ability to travel as required for sponsor meetings, conferences, and business needs.

What You'll Receive

• Competitive salary package
• Flexible work arrangements
• Industry-leading technology and systems
• Diverse, intellectually stimulating projects
• Clear career progression opportunities
• Supportive leadership team and collaborative culture
• Long-term stability with a growing global CRO

About Avance Clinical

Avance Clinical is a leading Australian CRO providing specialised drug development services to the biotechnology and pharmaceutical industries. With origins dating back to the 1980s, we have built an outstanding reputation for quality, service excellence and innovation. Today, we partner with biotech companies globally to accelerate the development of new medicines.