Medical Director, Clinical Development (Neurology)

Deciphera Pharmaceuticals, Inc.; United States; On-site; USD 248,000 - 341,000; Full time

Benefits offered by this job

Competitive salary

Annual bonus

Comprehensive benefits

Retirement plan

Job summary

Deciphera is seeking a Medical Director to provide clinical development leadership at the study level for one or more assets in early and/or late development. You will foster collaboration across functions, mentor clinical scientists as needed, and help drive strategic objectives and continuous improvement activities.

The role requires a Medical Degree or equivalent with 8+ years of combined academic and industry experience, including 3+ years in clinical trials, plus strong leadership and

Qualifications

• Medical Degree or equivalent with 8+ years of combined academic and industry experience.
• Includes at least 3+ years of work on clinical trials.
• Experience with clinical trial design, conduct, and medical monitoring.

Responsibilities

• Provide clinical development leadership to one or more programs.
• Contribute to clinical development strategy aligned with enterprise goals.
• Serve as medical monitor for studies and lead trial data review.

Skills

Clinical leadership

GCP/ICH knowledge

Regulatory awareness

Stakeholder management

Education

Medical degree or equivalent

Job description

Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera isleveragingits proprietary switch-control kinase inhibitor platform and deepexpertisein kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates fromDeciphera’splatform in clinical studies, QINLOCK® (ripretinib) isDeciphera’sswitch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. ROMVIMZA® (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatictenosynovialgiant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability.

The spirit of collaboration that has brought medications to life continues to guide how weoperate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together.

Deciphera offers competitive compensation, including equity-based compensation,and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, lifeinsuranceand a flexible spending account for either health care and/or dependent care.

The medical directorwill provide clinical development leadershipat the study levelfor one ormoreclinical stage assetsin earlyand/or late development.To achievedevelopment goals this individualwill foster collaboration withallied functions through outstandingcommunication, collaboration and coordination.Depending on business needs,the rolecouldinclude mentorship and managementof one or more clinical scientistsas well as contribution to business developmentand continuous improvementactivities.

Key Responsibilities:

• Provide clinical development leadershipto one or more programs75%
• Contribute toclinical developmentstrategy in alignment with enterprise goalsand management
• Serve as medical monitor for one or more studies
• Perform ongoing clinical trialdata review and cleaningin collaboration with clinical scienceand pharmacovigilance
• Attend and contribute tostudy teammeetings
• Presentclinical trial findings to management
• Authorclinical documents(protocol, investigator brochure)
• Authorclinical portionsofregulatory documents (IND, CTA,NDA, MAA or equivalent)
• Develop and manage relationships with key opinion leaders for clinical programs
• Organize, manage and lead Steering Committees and contribute to Strategic or Clinical Advisory Boards
• Contribute to writing of manuscripts, publications, or other documents intended for external audiences
• Contribute in an active and ongoing manner to the scientific, clinical, and commercial development of current and future product candidates
• Contribute to company culture and growth25%
• Foster communication, collaboration and coordination with other functions
• Contribute to maximizing synergistic collaboration between Ono and Deciphera
• Contribute to assessment of new internal or external targets by outlining clinical challenges andopportunities
• Support Medical Affairs activities as needed
• Participate in and/or coordinate cross-functional continuous improvement projects
• Act as an internal resource for functions requiring clinical input on select drug(s) including primary point of contact for clinical trial staff at study sites for clinical issues as well as regulatory, safety and other functions

• Medical Degree or equivalentwith 8+years ofcombinedrelevantacademic and industryexperience(post-medical school), including3+ yearsofwork onclinical trials.
• Experience with clinical trial design, conduct, and medical monitoring
• Understanding of GCP/ICH and regional/local regulations
• Familiarity with data review/analytics tools (Rave, J-Review,Spotifre,etc)
• Outstanding leadership, team, presentation, written and oral skills
• Collaborative and flexible in personal interactions at all levels of the company
• Ability to work proactively and effectively, with exceptional creative problem-solving skills
• Excellent strategic planning, organizational and communication skills
• Willingness to accommodate meetings across time zones as needed for project success
• Up to 30% travel

Preferred Capabilities

• Boardcertification in Nuerology
• Experiencein phases 3of clinical development
• Experienceinteracting withFDA andregulatoryagencies outside of the USA
• Experience inbasic or translational science

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $248,000-$341,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)

Benefits:

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.