Medical Director, Clinical Development – Multiple Myeloma

Connexion Systems + Engineering; Newton (MA); Hybrid; USD 216,000 - 308,000; Full time

Job summary

Connexion Systems & Engineering Inc. is seeking a Medical Director, Clinical Development focused on Multiple Myeloma for a fully remote 6+ month contract. You will serve as the primary medical lead, overseeing trial design, safety monitoring, and cross-functional collaboration from East Coast hours.

The role requires an MD/DO/PhD with 5+ years in oncology/hematology clinical development and hands-on medical monitoring. Strong leadership and regulatory experience are essential.

Qualifications

• MD, DO or PhD required.
• Minimum 5 years of clinical trial experience in pharma/biotech/academic settings.
• Experience in oncology/hematology clinical development, with exposure to Multiple Myeloma.

Responsibilities

• Serve as primary medical lead for Multiple Myeloma trials, guiding study design and reporting.
• Lead medical monitoring activities and safety review for study data.
• Support regulatory submissions and medical strategy with cross-functional teams.

Skills

Medical leadership

Clinical monitoring

Regulatory knowledge

Education

MD/DO/PhD

Job description

Title: Medical Director, Clinical Development – Multiple Myeloma (Remote Contract) Hiring Organization: Connexion Systems & Engineering Compensation, Benefits, and Employment Type Duration: 6+ month contract, possible extensions Pay rate: up to $190/hr, DOE Job Location: Boston, MA Work Model: 100% Remote (East Coast working hours) Schedule: flexible (40 hours) Job#: bh19734

Description: We are seeking an experienced Medical Director, Clinical Development to provide medical leadership and oversight for clinical trials focused on Multiple Myeloma. This is a fully remote, 6-month contract opportunity with the potential for extension, offering the chance to contribute to innovative oncology clinical development programs. The ideal candidate will bring a strong background in hematology/oncology clinical development, hands-on medical monitoring, and clinical trial leadership. This individual must be comfortable serving as both the primary Medical Monitor and medical lead for assigned clinical studies, working collaboratively with cross-functional teams to ensure patient safety, scientific integrity, and successful trial execution.

Key Responsibilities

Clinical Development & Study Leadership

Serve as the primary medical lead for assigned Multiple Myeloma clinical trials, providing strategic and scientific direction throughout study design, execution, and reporting. Lead medical monitoring activities, including ongoing evaluation of patient safety, adverse events, and clinical trial data. Collaborate with Clinical Operations, Regulatory Affairs, Data Management, Biostatistics, and other functional teams to support successful study execution. Contribute to the development of clinical study protocols, Investigator's Brochures, Clinical Development Plans, and other essential study documents. Provide clinical and scientific input into statistical analysis plans, informed consent forms, case report forms, and clinical study reports.

Medical Monitoring & Regulatory Support

Oversee medical and safety-related aspects of clinical trials, ensuring compliance with GCP and applicable regulatory requirements. Support preparation of regulatory submissions, including INDs, CTAs, safety reports, annual reports, and responses to regulatory authorities. Evaluate clinical data, identify emerging safety concerns, and provide medical guidance to study teams. Partner with investigators and external stakeholders to address clinical and scientific questions.

Scientific Collaboration & Program Development

Provide medical expertise to support clinical development strategy and lifecycle management activities. Collaborate with key opinion leaders (KOLs), academic investigators, and external research partners. Contribute to scientific publications, presentations, and clinical data dissemination. Stay current on emerging research, treatment approaches, and clinical developments in Multiple Myeloma and related hematologic malignancies. Support cross-functional scientific and medical initiatives as needed.

Qualifications Required

• MD, DO, or PhD.
• Minimum 5 years of clinical trial experience within the pharmaceutical, biotechnology, or academic research environment.
• Experience in oncology/hematology clinical development, preferably with direct exposure to Multiple Myeloma studies.
• Demonstrated experience serving as a medical lead for clinical trials or development programs.
• Hands-on experience performing medical monitoring activities, including clinical safety oversight and review of study data.
• Pharmaceutical or biotechnology industry experience managing clinical trials and/or clinical development programs.
• Strong knowledge of GCP, clinical trial design, regulatory requirements, and clinical research methodologies.
• Working knowledge of biostatistics, pharmacokinetics, and clinical data interpretation.
• Excellent written and verbal communication skills, with the ability to work independently and collaboratively across matrixed teams.

Additional Clinical Qualifications

At least 3 years of experience as an attending physician in oncology, hematology, internal medicine, or a relevant medical specialty, as applicable to physician candidates. Cancer research experience, including clinical data analysis and scient