Manufacturing Process Lead (2nd/3rd Shift)

Ring Inc; Princeton (NJ); On-site; USD 70,000 - 90,000; Full time

Benefits offered by this job

Pre-IPO equity

Annual bonus

Medical benefits

Dental benefits

Vision benefits

PTO

401(k)

Life insurance

AD&D coverage

Parental leave

Job summary

Orca Bio, a late-stage biotechnology company, is establishing manufacturing on the East Coast to ensure reliable delivery of high-precision cell therapies. The Manufacturing Process Lead will conduct cGMP manufacturing activities for clinical and commercial products, uphold quality standards, and document production in a regulated environment.

This role includes overseeing shift operations, developing procedures, training staff, and driving continuous improvement, with flexibility to work

Qualifications

• Bachelor’s degree in a science-related field required; master’s preferred.
• 2–3 years of experience in GMP manufacturing or process sciences.
• Experience with aseptic techniques.
• Familiarity with cell/gene therapy and human cell work.
• Flexibility to work outside standard hours to support site priorities.

Responsibilities

• Oversee routine manufacturing and occasional protocols.
• Develop procedures for cell separation technologies and aseptic connections.
• Serve as SME for cell therapy processes and new tech.
• Verify results and maintain detailed records.
• Prepare, maintain, troubleshoot, and operate instruments.
• Plan shifts, breaks, pass-downs, and make process decisions.
• Supervise in-room operations and delegate tasks.
• Complete deviations as required.
• Escalate issues appropriately.
• Review and support improvements to processes and SOPs.
• Provide training and coaching to employees.
• Other duties as assigned.

Skills

GMP Manufacturing experience

Aseptic techniques

Cell therapy knowledge

People leadership

Shift flexibility

Education

Bachelor's degree in science or related field

Job description

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

We are establishing manufacturing operations on the East Coast to ensure the consistent and reliable delivery of our high-precision cell therapy products. This site is essential to advancing our clinical pipeline and supporting future commercial availability of our life‑saving therapies.

The Manufacturing Process Lead conducts cGMP manufacturing activities to produce clinical and commercial cell therapies and helps to optimize Manufacturing processes. The Lead ensures and adheres to quality standards, regulatory requirements and aseptic production techniques. This position involves repeatedly executing manufacturing processes, cleaning and maintaining production equipment and workstations and documenting production activities in a highly regulated environment. This position also entails on‑shift oversight of production activities to ensure timely, efficient, and quality‑driven execution of each day’s objectives.

Essential Duties & Key Responsibilities

• Oversee execution of routine manufacturing and occasional scientific protocols
• Develop and refine procedures for cell separation technologies, sterile connections, and aseptic techniques
• Serve as subject matter expert for cell therapy processes and new technology
• Provide verification for results and ensure detailed records are maintained
• Prepare, maintain, trouble‑shoot, and operate instruments
• Plan the shift - including break management, shift pass‑downs, and process appropriate decisions
• Supervise in‑room operations and delegate individual tasks based on operator capacity
• Complete deviations
• Escalate issues appropriately
• Review and support continuous improvements of business processes, records, and SOPs
• Training and coaching employees
• Other duties as assigned

Minimum Qualifications

• Bachelor’s degree in a science related field (Biology, engineering, etc.) or related field, required. Master’s degree preferred
• 2‑3 years of experience in GMP Manufacturing, process sciences, or discovery
• Experience with aseptic techniques
• Familiarity with cell/or gene therapy, including working with human cells, cell characterization methods, or cell separation techniques
• Direct or indirect people leadership preferred
• Flexibility to work outside standard business hours when needed to support site priorities, deadlines, or critical business needs.

2nd Shift

• Monday - Friday, 4:00pm - 12:30am

3rd Shift

• Monday - Friday, 12:00am - 8:30am

Physical Demands

• Must have visual acuity of 20/20 (corrected or uncorrected) and normal color vision to safely perform critical tasks such as visual inspection of materials, equipment, and labeling, including distinguishing color‑coded components in a GMP environment.
• Must be able to meet cleanroom gowning requirements, including wearing full gowning (face coverings, gloves, hoods, goggles) for extended periods, as needed. Use of cosmetics (makeup, painted nails), jewelry, or facial piercings is not permitted in the cleanroom, and any skin conditions that cause shedding must be disclosed.

$70,000 - $90,000 a year

The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job‑related factors as permitted by law. For remote‑based positions, this range may vary based on your local market. Full‑time employment positions will also be eligible to receive pre‑IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits.