Manufacturing Excellence Lead

Manus Biosynthesis; Augusta (GA); On-site; < USD 1,000; Full time

Job summary

Manus Bio Inc. is seeking a Manufacturing Excellence Lead in Augusta, GA. You will head daily operations and drive a structured CI program across manufacturing, establishing standards and KPI monitoring to improve reliability and efficiency.

This role emphasizes hygienic design, GMP readiness, data-driven improvements, and cross‑functional collaboration with Quality, Engineering, and Maintenance to accelerate biomanufacturing excellence.

Qualifications

• Bachelor’s degree in Engineering, Manufacturing, or related field; Master’s preferred.
• 5–10 years in manufacturing focusing on CI/operational excellence.
• Experience implementing Lean, Six Sigma, TPM, or similar.
• Knowledge of hygienic design principles and GMP environments.
• Ability to lead cross-functional initiatives and drive measurable improvements.
• Strong analytical, problem-solving, and data-driven skills.
• Excellent communication, leadership, and organizational skills.
• Experience with manufacturing systems, data analytics, process control, AI/IIoT a plus.

Responsibilities

• Serve as manufacturing plant lead, overseeing daily operations.
• Develop and lead a structured CI program across manufacturing.
• Harmonize hygienic design, equipment cleanability and CIP effectiveness.
• Establish standard work, process discipline, and operational rigor.
• Define, monitor KPIs (OEE, yield, cycle time, downtime).
• Collaborate with Manufacturing, Quality, Engineering, Maintenance, and Process Technology teams.

Skills

Lean Six Sigma

Cross-functional leadership

Data-driven decision making

Analytical thinking

Communication skills

Education

Bachelor’s degree in Engineering, Manufacturing, or related field

Master’s degree preferred

Tools

Manufacturing systems

Data analytics

Process control

AI/IIoT

Job description

TerddHello

Driven by Purpose.
Guided by Principle.

And we need bright,
talented minds to join our journey.

We are an inclusive, interdisciplinary team drawn from around the world, dedicated to the sustainable production of materials, chemicals, and ingredients.

Our purpose is to accelerate the transition to BioAlternatives by delivering the benefits of biomanufacturing, today.

Our principles guide our journey and drive our commitment to ethical practices, scientific excellence, and innovation.

If you share our values and our passion, come join us.

See our open positions.

Manufacturing Excellence Lead Augusta, Georgia, United States, Full-Time

Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a self‑motivated and highly organized individual for a position that will specialize in and lead all laboratory operations at our Boston BioFacility.

We are looking for a Manufacturing Excellence Head to lead and institutionalize manufacturing excellence across operations. This role will be responsible for driving structured improvements in reliability, efficiency, and process performance through a disciplined, pillar‑based approach.

Why work at Manus:

• Opportunity – For motivated, results‑oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that comes with working on the cutting edge.

Key Responsibilities:

Serve as manufacturing plant lead, overseeing daily operations. Develop and lead a structured continuous improvement (CI) program across manufacturing, formally categorizing and managing all initiatives under three core pillars:

Hygienic Design Leadership

• Drive improvements in equipment design, cleanability, and sanitary engineering. Eliminate harborage points and ensure alignment with hygienic design standards to enhance product quality, reduce contamination risk, and improve clean‑in‑place (CIP) effectiveness

Consistent Operations Excellence:

• Establish and enforce standard work, process discipline, and operational rigor. Ensure robust SOP adherence, operator training programs, and repeatable execution of manufacturing processes to minimize variability and improve reliability.

Manufacturing Process Improvements:

• Lead yield optimization, cycle time reduction, waste elimination, process capability enhancement, technical upgrades, and new product startups.
• Define, implement, and monitor KPIs (OEE, yield, cycle time, downtime, batch success rate). Lead manufacturing data and stats preparation and reporting activities. Utilize data analytics to identify losses and track impact. Partner with Manufacturing, Quality, Engineering, Maintenance, and Process Technology teams to align initiatives to meet business objectives

Qualifications

• Bachelor’s degree in Engineering, Manufacturing, or related field (Master’s preferred).
• 5–10 years in manufacturing with focus on continuous improvement (CI), operational excellence, or reliability.
• Proven experience implementing Lean, Six Sigma, TPM, or similar methodologies.
• Strong understanding of hygienic design principles and GMP environments preferred.
• Demonstrated ability to lead cross‑functional initiatives and drive measurable improvements.
• Strong analytical, problem‑solving, and data‑driven skills.
• Excellent communication, leadership, and organizational skills.
• Experience with manufacturing systems, data analytics, process control, AI/IIoT a plus.

Preferred Qualifications

• Lean Six Sigma Certification (Green Belt, Black Belt, or higher).
• Experience in biomanufacturing, food, pharmaceutical, or chemical industries.
• Proven track record building and sustaining CI programs at scale.

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