Manufacturing Associate II, Oligo

Maravai LifeSciences; San Diego (CA); Vor Ort; USD 34.000 - 41.000; Vollzeit

Benefits dieser Stelle

Medical plans

RSU grants

Employee stock purchase plan

HSA/FSA options

Paid holidays & PTO

Zusammenfassung

Maravai LifeSciences is seeking a Manufacturing Associate II, Oligo to join the Oligo Manufacturing team in San Diego. You will execute daily manufacturing operations to produce research- and clinical-grade oligonucleotide products in ISO-class environments.

The role involves equipment setup, operation, cleaning, maintenance, troubleshooting, and batch documentation in compliance with GDP and SOPs. You will train junior staff and support continuous improvement initiatives to ensure timely

Qualifikationen

• Bachelor’s degree in a scientific discipline or equivalent experience.
• Experience following SOPs and maintaining manufacturing documentation.
• Experience in a cGMP environment and ISO cleanrooms.

Aufgaben

• Review production schedules and coordinate resources for timely execution.
• Prepare areas and equipment for cGMP production, including changeovers.
• Execute manufacturing processes per SOPs and batch records.
• Complete batch records, logs, and equipment records in GDP format.
• Operate and maintain manufacturing equipment and perform preventive maintenance.
• Train and mentor manufacturing personnel on procedures and timelines.
• Support onboarding of new equipment and processes with minimal supervision.
• Identify process issues and drive continuous improvement for quality.
• Collaborate with Process Development, Quality, and Engineering teams.
• Provide updates on progress and priorities to stakeholders.

Kenntnisse

SOPs

GDP

cGMP

Documentation

Troubleshooting

Cross-functional collaboration

Microsoft Office

Ausbildung

Bachelor’s degree in Chemistry, Biochemistry, Biology, Molecular Biology, or related

Tools

Microsoft Office

Jobbeschreibung

Who we are:

Maravai LifeSciences translates extraordinary science into everyday miracles, helping biotech, biopharma, and life sciences companies everywhere deliver novel vaccines, therapeutics, and diagnostics. We are global leaders in providing products and services within the fields of nucleic acid production and biologics safety testing to many of the world’s leading biopharma, vaccine, diagnostics, and cell and gene therapy companies.

At Maravai, we believe that diverse perspectives are the foundation of innovation.Through an inclusive andequitableculture where every team member is inspired to bring their best selves to work, we cultivate an environment in which we can lead together,providingdifferentiated value to our customers, and enabling the miracles of science.For over 35 years,Maravai’sportfolio companies have served as a catalyst for innovative, lifesaving technology for humanity. Pioneering nucleotide research since itsinception, we are now leading the way in the rapidly expanding mRNA market.

Your next role as a Miracle Maker

Maravai LifeSciences is seeking a #MiracleMaker to join our Oligo Manufacturing team as an Manufacturing Associate II, Oligo. The Manufacturing Associate II, Oligo is responsible for executing daily manufacturing operations to produce research- and clinical-grade oligonucleotide products in accordance with established procedures and quality standards. This role supports production activities within ISO-classified environments, including equipment setup, operation, cleaning, maintenance, and troubleshooting. The Manufacturing Associate II collaborates with cross-functional teams to ensure efficient production, adherence to cGMP requirements, and timely completion of manufacturing schedules. Additionally, this position provides technical guidance and training to junior manufacturing personnel while supporting continuous improvement initiatives.

How you will make an impact:

• Review production schedules, interpret manufacturing specifications, calculate material requirements, and coordinate resources to ensure timely execution of production activities.
• Prepare manufacturing areas, equipment, and materials for cGMP production activities, including project initiation and changeovers.
• Execute manufacturing processes in accordance with approved standard operating procedures (SOPs), batch records, and cGMP requirements.
• Accurately complete batch records, production logs, equipment records, and other required documentation in compliance with Good Documentation Practices (GDP).
• Operate, maintain, and troubleshoot manufacturing equipment, perform routine preventive maintenance, and coordinate repairs as needed.
• Author, review, revise, and execute batch records, SOPs, and other controlled manufacturing documents.
• Train, mentor, and provide technical guidance to manufacturing personnel, ensuring adherence to established procedures, quality standards, and production timelines.
• Support onboarding, qualification, and implementation of new manufacturing equipment and processes with minimal supervision.
• Identify and troubleshoot manufacturing process issues, evaluate production bottlenecks, and implement continuous improvement initiatives to enhance operational efficiency and product quality.
• Collaborate with Process Development, Quality, Engineering, and other cross-functional teams to support production requirements, process transfers, and manufacturing improvements.
• Provide timely written and verbal updates to supervisors and cross-functional stakeholders regarding production progress, technical challenges, and operational priorities.
• Maintain a safe, clean, and compliant manufacturing environment in accordance with established SOPs, safety requirements, and cGMP standards.
• Complete required training within established timelines and maintain compliance with applicable company policies and regulatory requirements.
• Perform plasmid DNA (pDNA) digestion, in vitro transcription (IVT), purification, and related manufacturing processes using specialized equipment in accordance with approved procedures.
• Execute enzymatic reactions and purification processes, including operation of purification systems, preparation of batch documentation, and implementation of SOPs.
• Perform gram-to-kilogram-scale chemical synthesis, including organic reactions, precipitation, salt exchange, extraction, deprotection, chromatography, fill-finish, and aliquoting of mRNA capping reagents, modified nucleoside triphosphates (NTPs), and other biotechnology raw materials.
• Perform synthetic oligonucleotide manufacturing activities, including chemical reactions, purification, processing, and associated batch documentation.
• Perform other functions and duties asrequired.

The skills and experience that you will bring:

• Bachelor’s degree in Chemistry, Biochemistry, Biology, Molecular Biology, or a related scientific discipline, or equivalent combination of education and relevant experience.
• Minimum of 2 years of experience in a biochemistry, biotechnology, or related manufacturing laboratory environment.
• Experience following, reviewing, and executing standard operating procedures (SOPs) and maintaining accurate manufacturing documentation.
• Strong organizational skills, attention to detail, and demonstrated ability to troubleshoot and resolve technical issues.
• Effective written and verbal communication skills, with the ability to collaborate across cross-functional teams.
• Ability to work independently, manage competing priorities, and meet established production timelines.
• Experience working in a current Good Manufacturing Practice (cGMP) environment, including ISO Class 7 or ISO Class 8 cleanrooms.
• Experience drafting, revising, and implementing SOPs, batch records, and other controlled manufacturing documents.
• Hands-on experience with chemical synthesis and purification processes involving mRNA capping reagents, modified nucleoside triphosphates (NTPs), or other biotechnology raw materials at scales ranging from 1 to 500 grams.
• Familiarity with manufacturing equipment operation, troubleshooting, preventive maintenance, and process improvement initiatives.
• Proficiency in Microsoft Office Suite, including Word, Excel, and Outlook.

The anticipated hourly rate for this position is $25 - $30 per hour. The offer will depend on multiple factors which may include the successful candidate’s skills, experience and other qualifications, as well as the location of the role.

#LI-Onsite

The benefits of being a #MiracleMaker:

• You have the potential to change,improve, and save lives around the world.
• You have the opportunity to be a partowner inMaravai through RSU grants andoptionalemployee stock purchase plans.
• Weoffer comprehensivemedical plansandHSA/FSAoptions.
• Fertility &family planningassistance.
• A variety ofadditionaloptional benefitsand insurance options, includingpet insurance.
• Retirementcontributions.
• Holidays & Paid Time Off.

Benefits may vary by region and employment type and do not apply to temporary employees or contractors. See a comprehensive list of benefits at Benefits & growth site at https://www.maravai.com/careers/benefits-and-growth/

MaravaiLifeSciences is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexualorientation,and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.

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