Manufacturing Associate

b.next; San Francisco (CA); On-site; USD 50,000 - 70,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k) plan

Job summary

A biotechnology firm in San Francisco is seeking a full-time Manufacturing Associate to support biomanufacturing of synthetic cellular components. Key responsibilities include media formulation, bacterial strain preparation, and quality control analytics. The ideal candidate should have keen attention to detail and a process-oriented mindset. The position offers competitive benefits and starts immediately in the Dogpatch neighborhood. If interested, please reach out via email.

Qualifications

• Experience in biomanufacturing processes is a plus.
• Ability to work in a fast-paced environment with a focus on quality.
• Willingness to learn new techniques and processes.

Responsibilities

• Run full-stack biomanufacturing for synthetic cellular components.
• Prepare media and buffer formulations.
• Manage bacterial strain preparations and biomass production.
• Conduct quality control analytics and inventory management.

Skills

Attention to detail

Process-oriented approach

Manual skills

Teamwork

Job description

b.next maintains Nucleus, the open source distribution and developer ecosystem for building synthetic cells. Instead of “editing” living cells, synthetic cell builders “compose” systems from individually validated components (DNA, RNA, proteins, small molecules). Designing, modeling, and testing compositions is much easier than living cells because you know and understand every component.

Our goal is to support the growing community of synthetic cell builders and to co-create a new field of biotechnology. To do so, we manufacture and validate components for developers and oversee the integration of new modules back into the Nucleus distribution. We also host Developer Notes, open-license preprints for rapidly and freely distributing data, protocols, and materials. In order to grow with the community, we need to prepare synthetic cell components at scale, and we need your help to do it.

b.next is looking to hire Manufacturing Associate(s) to run full-stack biomanufacturing for synthetic cellular components: media and buffer formulation and prep, bacterial strain preparation, biomass production, chromatography, polishing, quality control analytics, formulation, packaging, and shipping.

We’re putting together the team that will discover the next generation of biomanufacturing. We value both immediate skills and future potential. Do you geek out about process? Do you like making things with your hands? Have a keen eye for detail? A vision of the full picture? Do you like to learn? Like to teach? Let’s build together.

The team will run:

• Media and buffer formulation and prep
• E. coli strain preparation: DNA cloning, plating, small scale outgrowths, DNA sequencing
• Ferment: shake flasks and benchtop scale (≤10 L) reactors
• Preparatory and analytic FPLC
• Automated liquid handling and custom formulation
• Lyophilization: Formulation and machine operation
• QC: Proteins, DNA, RNA, Ribosomes
• Inventory Management
• Shipping and Logistics

Teammates will excel at the following:

• achieving high yield and quality preps
• identifying upgrades from the line

  This is a full-time, salaried position with benefits (medical, dental, vision, 401(k)) based in the Dogpatch, San Francisco, starting immediately. If this is your team, email [e-mail].