Manager, Upstream Process Development and Scale-up

Radiometer; Marlborough (MA); On-site; USD 126,000 - 150,000; Full time

Benefits offered by this job

Medical/dental/vision insurance

401(k)

Paid time off

Job summary

Cytiva in Marlborough, MA, is seeking an Upstream Manager to lead Fast Trak Process Development services. You will oversee upstream development, scale-up, tech transfer for biologics and related modalities, guiding cross-functional teams and ensuring robust documentation.

The role requires a PhD/MS with 10+ years in biologics, strong leadership, and ability to travel. A DBS-based approach and collaboration with diagnostics and pharma teams are essential.

Qualifications

• Bachelor’s degree or higher in chemical engineering, molecular biology, biochemistry or related discipline.
• 10+ years of relevant experience in biologics with 2+ years in leadership or management roles.

Responsibilities

• Lead planning, execution, and delivery of upstream process development, scale-up, and technology transfer for biologics and related modalities.
• Provide technical oversight and leadership for cell culture bioreactor operations and process characterization.
• Support development of new service offerings and ensure robust documentation (SOPs, study plans, batch records, reports).
• Collaborate with downstream, analytics, applications, automation, R&D, and PMO teams to ensure project execution and KPI achievement.

Skills

Upstream process development

Scale-up

Technology transfer

Mammalian cell culture

Project management

Technical writing

Education

Bachelor's degree in chemical engineering, molecular biology, biochemistry

Job description

Upstream Manager – Fast Trak Process Development Services Bring more to life. Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Cytiva, one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact. You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact - innovating at the speed of life. Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself and us - working on challenges that truly matter with people that care for each other, our customers, and their patients. Take your next step to an altogether life-changing career. Learn about the Danaher Business System which makes everything possible.

What you’ll do

• Technical and Business Leadership: Lead planning, execution, and delivery of upstream process development, scale-up, and technology transfer activities for biologics, viral vectors, plasmid DNA, mRNA, and other advanced therapy modalities.
• Provide technical oversight and scientific leadership for cell culture bioreactor operations, process characterization and scale-up activities, and serve as a technical subject matter expert (SME) during customer meetings, project reviews, technical investigations, risk assessments, and troubleshooting activities.
• Support the development of innovative service offerings, technologies, and workflows that expand Fast Trak capabilities and customer value.
• Support proposal development, scope definition, technical reviews, customer presentations, and drive robust documentation practices including SOPs, study plans, batch records, investigations, technical reports, and technology transfer documentation.
• Partner closely with downstream, analytics, applications, automation, R&D, commercial, and PMO teams to ensure successful project execution and foster scientific collaborations within Fast Trak PD, cross-functional teams, and customers to drive efficient execution of internal and external KPIs.
• Lead and support workforce planning, talent development, recruitment, onboarding, succession planning, and ensure effective resource allocation and project prioritization to meet customer and business objectives.
• Drive on-time delivery, quality, productivity, continuous improvement initiatives, and customer satisfaction metrics utilizing Danaher Business System (DBS) principles and tools.

Who you are

• Bachelor’s degree or higher (MS or PhD preferred) in chemical engineering, molecular biology, biochemistry, or related discipline with 10+ years of relevant experience in biologics with 2+ years of direct experience leading technical teams and/or people management responsibilities.
• Demonstrated hand-on expertise in upstream process development, scale-up, technology transfer, and mammalian cell culture operations ranging from laboratory to pilot scale.
• Experience managing customer-facing projects and cross-functional teams with strong technical writing and presentation skills.
• People leader that fosters a culture of safety, accountability, inclusion, collaboration, continuous improvement, and scientific excellence.

Travel and Work Environment

• Ability and willingness to work in laboratory and pilot-scale environments, including BSL-2 laboratories when required.
• Ability and willingness to travel domestically and internationally to support customer engagements, technology transfers, training, and conferences.
• Flexibility to support occasional off-hours activities associated with critical project milestones and run schedules.

The salary range for this role is $126,000.00 - $150,000.00. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. We may ultimately pay more or less than the posted range. This range may be modified in the future. This job is also eligible for bonus/incentive pay.

We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.

Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.

For more information, visit www.danaher.com.

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Danaher is a leading global life sciences, biotechnology, and diagnostics innovator, helping to solve many of the world’s most important health challenges, ultimately improving quality of life for billions of people today, while setting the foundation for a healthier, more sustainable tomorrow.

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