Manager, Tax

Arrowhead Pharmaceuticals, Inc.; San Diego (CA); On-site; USD 120,000 - 180,000; Full time

Job summary

Arrowhead Pharmaceuticals, Inc. in Pasadena or San Diego, CA seeks a Tax Manager to oversee tax compliance, reporting, and planning. The role partners with Finance, Accounting, Legal, and external advisors to ensure accurate filings and alignment with business initiatives. In-office role, five days a week.

The ideal candidate has a CPA and/or Master’s in Tax, 5+ years of progressive tax experience, and strong ASC 740 knowledge for domestic and international matters.

Qualifications

• Bachelor’s degree in Accounting, Finance, Tax, or related field.
• CPA and/or Master’s in Tax, Accounting or related discipline.
• 5+ years of progressive tax experience.
• Strong ASC 740 knowledge and corporate tax compliance.
• Experience with third-party tax service providers or external advisors.
• Strong analytical and communication skills.

Responsibilities

• Oversee global tax provision work and ASC 740 disclosures.
• Manage US federal/state and foreign corporate income tax filings.
• Prepare and review indirect taxes (sales/use tax, VAT/GST, property tax).
• Coordinate with third-party tax providers on credits, transfer pricing, planning.
• Assist with tax audits and inquiries.
• Maintain documentation of tax positions and internal controls (SOX).
• Support cross-functional initiatives and policy development.

Skills

ASC 740 knowledge

Tax compliance

Analytical thinking

Attention to detail

Cross-functional collaboration

Communication skills

Education

Bachelor’s degree in Accounting, Finance, Tax, Business, or related field

CPA and/or Master’s in Taxation/Accounting

Tools

Microsoft Excel

Microsoft Office

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Tax Manager will oversee the company’s tax compliance, reporting, and strategic tax planning activities. This role is responsible for managing global tax provision work, corporate income tax filings, indirect tax matters, tax audits, internal controls, and relationships with external tax advisors. The Tax Manager will partner cross-functionally with Finance, Accounting, Legal, and external service providers to ensure accurate and timely tax reporting, compliance with applicable regulations, and effective support of business initiatives.

This position requires strong technical tax knowledge, attention to detail, sound judgment, and the ability to manage multiple priorities in a growing, fast-paced organization. The ideal candidate is hands-on, collaborative, analytical, and comfortable both leading tax-related projects and executing detailed tax work.

This role is based in Pasadena or San Diego, CA with an expectation to be in office 5 days a week.

Responsibilities

• Manage, and/or review global tax provision and footnote disclosures in accordance with ASC 740.
• Manage and review all aspects of US federal, state and foreign corporate income taxes prepared by third-party service providers. This includes returns, extensions, estimated payments, etc.
• Prepare, review and/or manage indirect taxes (e.g. Sales and Use tax, VAT/GST, property taxes, etc.).
• Manage third party service providers. Examples of projects are R&D credits, state (nexus, sourcing, apportionment, etc.), transfer pricing, structuring/planning, international expansion, Section 382.
• Assist with tax audits and other tax-related inquiries.
• Responsible for documenting policies, tax positions, calculations.
• Maintain internal controls to comply with SOX regulations.

Requirements

• Bachelor’s degree in Accounting, Finance, Tax, Business, or a related field.
• CPA and/or Master’s in Business Taxation, Taxation, Accounting, or a related discipline.
• 5+ years of progressive tax experience.
• Strong working knowledge of ASC 740 and corporate income tax compliance.
• Experience preparing, reviewing, or managing U.S. federal and state corporate income tax filings, extensions, estimated payments, and related compliance activities.
• Experience working with third-party tax service providers or external advisors.
• Working knowledge of indirect taxes, including sales and use tax, VAT/GST, property tax, or similar tax areas.
• Experience supporting tax audits, tax inquiries, documentation of tax positions, and internal control processes.
• Strong analytical, organizational, written, and verbal communication skills.
• Advanced proficiency in Microsoft Excel and strong working knowledge of Microsoft Office applications.
• Ability to manage multiple priorities, meet deadlines, and work effectively in a collaborative, cross-functional environment.
• Demonstrated ability to problem-solve, take initiative, and operate with a hands-on, team-oriented approach.

Preferred

• International tax experience
• Biotechnology or life science industry experience

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.