Manager, Statistical Programming

Supernus Pharmaceuticals, Inc.; Rockville (MD); On-site; USD 100,000 - 130,000; Full time

Benefits offered by this job

Health insurance

Dental benefits

401k company match

Paid time off

Job summary

A leading biopharmaceutical company in Maryland is seeking a Manager of Statistical Programming to lead statistical programming activities for clinical projects. The role focuses on ensuring high-quality analysis deliverables, developing with SAS, and guiding junior programmers. Candidates should have a solid background in Life Sciences, strong SAS programming skills, and a minimum of five years in a clinical research setting. Competitive salary range is offered between $100,000 to $130,000.

Qualifications

• Minimum five years of experience in a pharmaceutical/Clinical Research organization.
• Ability to develop SAS programs and macros to create SDTM, ADaM, and TFLs.
• Working knowledge of CDISC standards with hands-on experience.

Responsibilities

• Lead statistical programming activities for clinical projects.
• Ensure timely delivery of quality clinical trials analysis deliverables.
• Mentor and guide junior programmers.

Skills

SAS programming

Statistical Analysis

Problem solving

R proficiency

Communication skills

Attention to detail

Education

Bachelor's degree in Life Sciences or related field

Master's degree in a related field

PhD in a related field

Tools

SAS

CDISC standards

Job description

Supernus Pharmaceuticals is an award-winning biopharmaceutical company with more than 30 years of experience in developing and commercializing products that treat central nervous system (CNS) diseases. At Supernus, we develop innovative products that help treat neurological and psychiatric conditions. We currently have 8 products in the market that are making a real impact on patient outcomes.

Job Summary

The Manager of Statistical Programming will lead and support statistical programming activities for clinical projects conducted by Supernus Pharmaceuticals. This role ensures the timely delivery of high-quality clinical trials analysis deliverables by adhering to established standards and processes.

Essential Duties & Responsibilities

• Oversees all statistical programming activities for an in-house clinical study, ensuring compliance with Supernus standards.
• Reviews and provides input on Statistical Analysis Plans (SAPs) to ensure alignment with study objectives.
• Develops Study Data Tabulation Models (SDTMs) and Arrangement of variables (ADaM) mapping specifications in accordance with CDISC SDTM Implementation Guides (SDTM IG).
• Programs and validates SDTM and ADaM datasets using SAS programs.
• Prepares SDTM and ADaM submission packages, including define.xml, review guides, and annotated eCRF.
• Generates and validates Tables, Figures, and listings (LTFs) according to approved specifications.
• Validates outsourced datasets provided by vendors and performs ad hoc analyses as needed.
• Contributes to the development and enhancement of programming standards and workflows.
• Mentors and guides junior programmers to foster skill development and ensure quality deliverables.
• Employee management responsibilities assigned as needed.
• Performs other duties as assigned.

Supervisory Responsibilities

• Provides leadership and management in an effective manner consistent with Company Values towards defined Corporate Objectives.
• Understands Company Policy and procedure to be able to guide direct reports appropriately.

Knowledge & Other Qualifications

• Bachelor’s degree in Life Sciences, computer science, mathematics, statistics, or related quantitative/analytical field with a minimum of five years of experience in a pharmaceutical/Clinical Research organization; a master’s degree in a related field with a minimum of three years of experience; or a PhD with one year of experience.
• Proficiency in R is a plus.
• Demonstrated ability to develop SAS programs and macros to create SDTM, ADaM, and TFLs.
• Demonstrated ability to identify and solve moderately complex problems.
• Working knowledge of CDISC standards with hands‑on experience in generating define packages.
• Familiarity with ICH guidelines and FDA guidance related to clinical study conduct and data submission.
• Familiarity with statistical methods that apply to Phase I‑IV clinical trials.
• Excellent written and oral communication skills including grammatical/technical writing skills.
• Excellent attention to detail and accuracy.

Other Characteristics

• Ability to work independently and as part of a team and maintain high ethical standards of integrity and quality.
• Ability to have an innovative and dynamic approach to work.
• A self‑starter able to work independently but comfortable working in a team environment.
• Ability to consistently exhibit Supernus Values in interactions with employees at all levels of the organization, vendors, customers and others.
• Capable of performing other duties as assigned by Management.
• Authorized to legally work in the United States without visa sponsorship.

Physical Requirements/Work Environment/Travel Requirements

• Sedentary work. Exerting up to 10 pounds of force occasionally and/or carrying objects. Sedentary work involves sitting most of the time.
• The worker is required to have close visual acuity to perform an activity such as: preparing and analyzing data and figures; transcribing; viewing a computer screen, iPad, or other electronic device; and extensive reading.
• The worker is not substantially exposed to adverse environmental conditions.

Compensation

At Supernus, we offer a competitive compensation package that reflects your experiences and contributions. The expected salary range for fully qualified candidates applying for this role is $100,000 to $130,000. This range is what the Company reasonably expects to offer for the position and is not reflective of the full compensation scale of the role. This range may be modified in the future. An individual’s salary within the range is based on multiple factors, which may include and are not limited to education, relevant experience, knowledge, length of industry experience and organizational needs.

You also will be able to participate in a competitive benefits package, including but not limited to: health, dental, vision, paid time off, 401k company match, company paid life insurance and health and wellness benefits. The total compensation package for this position also includes other compensation elements such as stock equity awards, employee stock purchase programs and participation in our Company’s discretionary annual bonus program.

Supernus Pharmaceuticals is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, national origin, disability, protected veteran status, age or any other characteristic protected by law.