Manager or Senior Manager, Clinical Outsourcing

Kymera Therapeutics; Boston (MA); On-site; USD 140,000 - 190,000; Full time

Job summary

Kymera Therapeutics is seeking a senior professional to oversee clinical outsourcing contracts, vendor selection, and financial tracking across a fast-paced biotech environment.

You will negotiate MSAs and SOWs, manage RFP processes, and collaborate with finance and legal to ensure project success and cost efficiency.

Qualifications

• 5+ years in clinical outsourcing or related operations.
• Proven track record in pricing and contract negotiations.
• Strong cross-functional collaboration with legal and finance teams.

Responsibilities

• Negotiate and manage contracts, including MSAs, SOWs, and Change Orders.
• Oversee RFP processes and vendor evaluation.
• Manage budgets and track expenses across studies.
• Lead vendor selection for CRO and ancillary services (eCOA/ePRO, labs, imaging, IRB, pharmacovigilance).
• Prepare financial analyses for senior leadership on vendor awards.

Skills

Vendor negotiations

Project management

Cross-functional collaboration

Budget management

Clinical outsourcing knowledge

Tools

MSA & SOW drafting

RFP processes

Contract negotiation

Job description

Who we are

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visitwww.kymeratx.com or follow us onX (formerly Twitter)orLinkedIn.

How we work

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll make an impact

• Negotiate and manage contracts, including Master Service Agreements (MSAs), Statements of Work (SOWs), and Change Orders.
• Oversee the Request for Proposal (RFP) processes, ensuring thorough evaluation and selection of vendors.
• Manage all aspects of clinical contracts and change orders throughout the clinical study lifecycle.
• Lead negotiations with vendors to secure beneficial contract terms and cost efficiency for Kymera while ensuring project requirements and timelines are met.
• Develop and review SOWs in collaboration with legal and finance stakeholders.
• Manage vendor selection and contracting across CRO and ancillary vendor categories, including eCOA/ePRO, central laboratory, imaging, IRB, and pharmacovigilance vendors.
• Conduct comparative analysis on vendor budgets to evaluate bids and identify negotiation opportunities.
• Negotiate beneficial payment schedules and terms.
• Track study and project budgets, including monitoring actuals and identifying variances.
• Collaborate closely with finance for budgeting and forecasting.
• Prepare comparative budget analyses to support senior leadership vendor-award decisions.
• Ensure financial accountability by managing budgets, tracking expenses, and providing regular financial reports.
• Attend study team meetings and interact with cross-functional stakeholders to ensure appropriate specifications and scope are included in agreements.
• Collaborate with various stakeholders across the organization, including finance and legal, to ensure smooth communication and effective project management.
• Manage multiple priorities effectively in a fast-paced and dynamic environment.
• Foster long-term working relationships with Kymera vendors.
• Deliver projects on time and within budget, ensuring high standards of quality and compliance.
• Understand and manage the complexities of clinical trials, including vendor selection, contract negotiation, and financial tracking.
• Lead and manage special initiatives in support of the clinical outsourcing function to support continuous improvement.

Skills and experience you’ll bring

• 5+ years' experience within clinical outsourcing or a closely related clinical operations role (Manager level); 8+ years for consideration at the Senior Manager level.
• Demonstrated track record of effective pricing and contract negotiations.
• Strong ability to work with stakeholders across the organization, including finance and legal teams.
• Excellent project management skills, with a history of on-time project delivery.
• Solid understanding of clinical trials and the processes involved in clinical outsourcing.
• Proven experience in negotiating and managing contracts, including MSAs, SOWs, and Change Orders.
• Experience in managing RFP processes and leading special initiatives.
• Strong financial management skills, with the ability to manage budgets and track expenses effectively.
• Ability to thrive in a fast-paced and dynamic work environment.
• Experience within a biopharmaceutical or clinical-stage biotech environment strongly preferred.
• Experience with Central Laboratory Services contracting is preferred.
• Comfort preparing financial analyses and materials for senior/executive leadership audiences.

Equal Employment Opportunity

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.

Compensation

• Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
• The anticipated base salary range for this role is $115,000– $215,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
• Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.