Manager of Statistical Programming New US Remote

Natera, Inc.; Northern (KY); Hybrid; USD 132,000 - 165,000; Full time

Benefits offered by this job

Competitive Benefits

Free cfDNA testing info

401k benefits

Commuter benefits

Employee referral program

Job summary

Natera is seeking a Manager of Statistical Programming to lead the statistical programming deliverables for oncology trials, with strong R programming and clinical trials background. You’ll contribute to analyses for regulatory submissions and help maintain a controlled programming environment.

You will oversee ADS and TLF development, build R packages and Shiny dashboards for data review and monitoring, and collaborate cross-functionally to drive best practices in statistical programming.

Qualifications

• Bachelor’s degree in statistics, mathematics, computer science or a related field.
• 5+ years of related experience, including 3+ years in clinical trial analysis.
• At least 3 years of R programming experience, including package development.

Responsibilities

• Lead and oversee statistical programming deliverables, including ADS and TLF, ensuring data integrity and regulatory compliance.
• May manage a team of statistical programmers and contribute hands-on to programming work.
• Act as primary programming lead for regulatory submissions (510(k), CTA/CDx, PMA).
• Maintain programming infrastructure, including R package development, validation, and maintenance.
• Develop R Shiny dashboards to support data review and study monitoring.
• Promote statistical programming development and validation best practices.
• Work cross-functionally with Biostats, Data Management, Clinical Science and other functions.

Skills

Leadership

Cross-functional collaboration

Regulatory knowledge

Education

Bachelor's in Statistics/Math/CS

Tools

R programming

R package development

ADS generation

TLF generation

Job description

This is an exciting opportunity to participate in advancing Natera’s oncology product portfolio of cutting‑edge diagnostic tests. As Manager of Statistical Programming, you will leverage your strong R programming skills and clinical trials background to contribute to the analysis and reporting of clinical trials supporting multiple regulatory submissions.

Primary Responsibilities:

• Lead and oversee statistical programming deliverables, including ADS (Analysis Datasets) and TLF (Table, Listings and Figures), ensuring data integrity and regulatory compliance with ICH, GCP, and FDA 21 CFR Part 11.
• May manage a team of statistical programmers, taking responsibility for their technical and professional development, while contributing hands‑on to programming work.
• Act as primary programming lead for regulatory submissions (e.g., 510(k), CTA/CDx, and PMA), ensuring all deliverables meet rigorous global standards.
• Maintain programming infrastructure, including R package development, validation, and maintenance in a controlled environment.
• Develop R Shiny dashboards that support data review, study monitoring, and exploration of analysis results.
• Promote statistical programming development and validation best practices.
• Work cross‑functionally with Biostats, Data Management, Clinical Science, and other functions as necessary.

Qualifications:

• Bachelor’s in Statistics, Mathematics, Computer Science, or a related field.
• 5+ years of related experience, with at least 3 years of experience in Clinical Trial analysis.
• At least 3 years of R programming experience, including package development.

Knowledge, Skills, and Abilities:

• Proficient in R programming, including building and maintaining packages.
• Experience in analysis dataset and TLF generation.
• Prior experience in NGS, genetics, and/or oncology diagnostics preferred.
• Experience maintaining statistical computing environments a plus.

Remote USA

$132,000 - $165,350 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell‑free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world‑class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits – Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

If you are based in California, we encourage you to read this important information for California residents.

Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.