Manager, IT G&A Applications Cambridge, MA

Amylyx Pharmaceuticals, Inc.; Cambridge (MA); Hybrid; USD 119,000 - 134,000; Full time

Job summary

Amylyx Pharmaceuticals, Inc. is seeking a Manager of IT Business Applications for G&A to support NetSuite and related systems across HR, Finance, Legal, and Procurement.

The role partners with cross-functional teams to improve processes, user experiences, and system hygiene while ensuring regulatory compliance. The position is based in Cambridge, MA with remote opportunities in the United States and periodic in-person collaboration.

Qualifications

• Bachelor’s degree in a related field or equivalent experience.
• 5+ years of IT experience with business applications and analysis.
• 3+ years of hands-on ERP experience, NetSuite preferred.

Responsibilities

• Support day-to-day NetSuite activities across HR, Finance, Legal, and Procurement.
• Lead implementations, administration, and ongoing support of G&A apps.
• Partner with stakeholders to translate requirements into system solutions.
• Support change control, testing, and audit readiness as needed.

Skills

NetSuite

ERP experience

Data analysis

Stakeholder comms

Education

Bachelor’s degree

Tools

NetSuite Inventory Management

Job description

Manager, IT Business Applications - G&A Systems

Cambridge, MA

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

We are seeking a highly organized, systems-minded Manager of IT Business Applications for G&A to support day-to-day operations for Amylyx’s HR, Finance, Legal, and Procurement systems, with NetSuite ERP as the primary focus. This customer-facing role will support, maintain, and enhance business applications partner cross-functionally to improve processes, and user experience.

Responsibilities

• Support day-to-day NetSuite activities such as purchasing, receiving, fulfillment, warehouse, and other related Finance/Supply Chain processes.
• Support successful implementations, administration, and ongoing support of Amylyx G&A business applications.
• Partner with HR, Finance, Legal, Procurement, Supply Chain, and IT stakeholders to gather requirements, analyze workflows, document business processes, and translate needs into practical system and operational solutions.
• Support change management, governance, testing, user acceptance activities, and implementation of enhancements in accordance with business needs and IT procedures.
• Ensure appropriate IT processes, procedures, standards, controls, and documentation practices are followed, including support for audit activities as needed.

Required Qualifications

• Bachelor’s degree in computer science, information systems, business, or a related field.
• 5+ years of IT experience with progressively increasing technical, business analysis, and application support responsibilities
• 3+ years of hands‑on ERP experience, such as enhancement projects, data management, and process improvements. NetSuite strongly preferred.
• Hands‑on experience with NetSuite Inventory Management or comparable ERP functionality, including item master data, inventory adjustments, transfers, receipts, fulfillments, and inventory reporting.
• Ability to troubleshoot system and transaction issues, identify root causes, and partner with business users to resolve errors.
• Excellent verbal and written communication skills, with the ability to interact professionally with executives, managers, subject matter experts, business users, IT colleagues, and external partners.
• Strong customer service orientation, attention to detail, data accuracy, and commitment to strong system hygiene.
• Experience supporting regulated environments, such as pharmaceutical, biotech, medical device, or SOX‑controlled environments.

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
• Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis.
• You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested, which may include travel by air, driving or public transportation.
• You must have access to work in setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communication via video conference, etc.) at your remote location.

#LI-TD1

Compensation

The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.

$119,000 - $134,000 USD

Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy‑related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.