Lead Translational Biomarker Scientist for Muscle Disease AI

Cytokinetics; San Francisco (CA); On-site; USD 203,000 - 236,000; Full time

Benefits offered by this job

Equity in stock options

Comprehensive health, dental, vision

401k with employer match

Learning stipends

Job summary

Cytokinetics is seeking a highly motivated computational scientist to lead translational biomarker discovery at the intersection of human genetics, multi-omics, and AI/ML. You will identify biomarkers that diagnose disease, predict progression, and anticipate outcomes in cardiac and skeletal muscle disorders.

Collaborating with experimental biologists and clinical research, you will translate patient insights into discovery and bring discovery toward the clinic, as a hands-on leader applying AI

Qualifications

• Ph.D. in Computational Biology, Human Genetics, Bioinformatics, or related field with post‑doc/industry experience.

Responsibilities

• Integrate genomic, transcriptomic, proteomic and single-cell data to trace how genetic variation drives molecular changes in muscle disease.
• Discover and validate diagnostic and prognostic biomarkers using omics and longitudinal clinical data.
• Develop AI/ML methods linking molecular profiles with imaging and clinical phenotypes to define patient subgroups.
• Investigate disease heterogeneity and genotype-phenotype discordance to uncover modifier pathways.
• Lead translational applications of LLMs and agents with benchmarking.

Skills

Genomics data analysis

Transcriptomics

Single-cell analysis

R and Python

AI/ML methods

LLMs

Education

Ph.D. in Computational Biology, Human Genetics, Bioinformatics or related field

Tools

GWAS data processing

Longitudinal data analysis

Biomarker discovery pipelines

Job description

Cytokinetics is seeking a highly motivated computational scientist to lead translational biomarker discovery at the intersection of human genetics, multi-omics, and AI/ML. You will identify biomarkers that diagnose disease, predict progression, and anticipate outcomes in cardiac and skeletal muscle disorders.

Collaborating with experimental biologists and clinical research, you will translate patient insights into discovery and bring discovery toward the clinic, as a hands-on leader applying AI