Lead System Engineer - Aerosol Delivery & Lab Systems

System One, Inc.; Pittsburgh (Allegheny County); On-site; USD 110,000 - 150,000; Full time

Job summary

System One, Inc. is seeking a Lead System Engineer onsite in Pittsburgh, PA. The role targets development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant platforms.

Responsibilities include design, prototyping, fabrication process optimization, materials evaluation, and performance validation. Collaboration across multidisciplinary teams and thorough technical documentation are required.

Qualifications

• Bachelor’s degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field.
• Minimum of 3 years of relevant experience in device design, prototyping, or fabrication.
• Experience with engineering design tools (e.g., CAD software).
• Strong problem-solving skills and attention to detail.
• Ability to work effectively in multidisciplinary research and engineering environments.

Responsibilities

• Design, prototype, and refine biomedical devices and components supporting advanced experimental system.
• Develop and optimize fabrication processes to ensure consistency, quality, and scalability.
• Contribute to selection and evaluation of materials, fabrication methods, and assembly workflows.
• Perform testing and validation of device performance, including durability, reproducibility, and functional integrity.
• Collaborate with scientific and engineering teams to align device design with experimental requirements.
• Maintain documentation related to design iterations, fabrication processes, and quality control.
• Troubleshoot device-related issues and implement design improvements.
• Support coordination of engineering activities across multidisciplinary teams and contribute to project execution.
• Contribute to preparation of technical documentation, reports, and related materials.

Education

Bachelor’s degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field

Master’s or Ph.D. in a relevant engineering discipline

Tools

CAD software

Job description

System One, Inc. is seeking a Lead System Engineer onsite in Pittsburgh, PA. The role targets development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant platforms.

Responsibilities include design, prototyping, fabrication process optimization, materials evaluation, and performance validation. Collaboration across multidisciplinary teams and thorough technical documentation are required.