Lead Statistical Programmer — AI-Driven Clinical Data Leader

Biopharma Careers

Durham (NC)

On-site

USD 130,000 - 180,000

Full time

14 days+

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Job summary

ViiV Healthcare seeks a Principal Statistical Programmer to lead programming activities for multiple clinical studies, ensuring high-quality development, validation, and delivery of complex analyses. The role drives technical excellence, regulatory compliance, and data-driven strategy, while mentoring junior staff and shaping study design.

Responsibilities include leading programming packages, adopting modern tools, and supporting QA, CDISC standards, and TMF governance.

Qualifications

Bachelor’s degree in Statistics, Computer Science, or a related field.
Expertise in R programming.
6+ years of clinical programming experience.
5+ years of experience in the Pharmaceutical or Biotechnology industry.
Experience using generative AI tools and coding assistants (e.g., GitHub Copilot, Codex, and Claude) to improve programming efficiency, automation, code quality, and analytical workflows in clinical programming.

Responsibilities

Lead programming for studies, ensuring efficient development and validation of analysis packages.
Identify and implement improvements, including use of AI/ML.
Maintain governance and oversee TMF compliance.
Communicate technical concepts, risks, and timelines clearly to stakeholders.
Mentor junior programmers and share best practices internally and externally.
Support sprint planning and project delivery across studies.
Collaborate cross-functionally and manage data access appropriately.
Provide technical input on programming strategies and study design.