Lead Scientist Radiopharmaceutical CMC Development

Bristol-Myers Squibb; Indianapolis, Northern (IN, KY); Hybrid; USD 124,000 - 151,000; Full time

Benefits offered by this job

Health Coverage

401(k) with company match

Paid time off

Job summary

RayzeBio, a Bristol Myers Squibb subsidiary, seeks a Principal Scientist to lead radiopharmaceutical development and CMC activities from bench to clinic. You will guide formulation development, IND-enabling studies, and scale-up, collaborating across discovery, regulatory, and manufacturing teams.

The role emphasizes cross-functional leadership, technical writing, and program management, with up to 20% travel. Indianapolis-based on-site role with competitive compensation and benefits.

Qualifications

• Ph.D., M.S., or B.S. in Chemistry, Chemical Engineering, Pharmaceutical Sciences, or related field with industry experience.
• 8+ years of drug development, manufacturing, CMC or related pharmaceutical experience.
• Demonstrated experience in radiopharmaceutical formulation development, process development, and GMP manufacturing.

Responsibilities

• Provide scientific and technical leadership across radiopharmaceutical drug product development and GMP manufacturing operations.
• Lead and execute IND-enabling studies and support regulatory submissions (IND/NDA).
• Drive technology transfer from preclinical to clinical manufacturing environments.
• Collaborate with Regulatory, Quality, and R&D to align program milestones with corporate objectives.
• Mentor junior scientists and support commercialization activities for radiopharmaceuticals.

Skills

GMP regulations

Cross-functional collaboration

Technical writing

Project management

Radioisotope handling

Regulatory submissions

Education

PhD/MS/BS in Chemistry/ Chemical Engineering/ Pharmaceutical Sciences

Tools

Automated synthesis platforms

Job description

RayzeBio, a Bristol Myers Squibb subsidiary, seeks a Principal Scientist to lead radiopharmaceutical development and CMC activities from bench to clinic. You will guide formulation development, IND-enabling studies, and scale-up, collaborating across discovery, regulatory, and manufacturing teams.

The role emphasizes cross-functional leadership, technical writing, and program management, with up to 20% travel. Indianapolis-based on-site role with competitive compensation and benefits.